Viruses and Hodgkin lymphoma: No evidence of polyomavirus genomes in tumor biopsies
The epidemiology of young adult Hodgkin lymphoma (HL) suggests that delayed exposure to a common childhood pathogen may be involved in disease pathogenesis. The Epstein-Barr virus (EBV) is associated with a proportion of cases but cases of young adult HL in westernized countries are less frequently...
Gespeichert in:
| Veröffentlicht in: | Leukemia & lymphoma 2006-07, Vol.47 (7), p.1315-1321 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1321 |
|---|---|
| container_issue | 7 |
| container_start_page | 1315 |
| container_title | Leukemia & lymphoma |
| container_volume | 47 |
| creator | Wilson, Katherine S. Gallagher, Alice Freeland, June M. L. Shield, Lesley A. Jarrett, Ruth F. |
| description | The epidemiology of young adult Hodgkin lymphoma (HL) suggests that delayed exposure to a common childhood pathogen may be involved in disease pathogenesis. The Epstein-Barr virus (EBV) is associated with a proportion of cases but cases of young adult HL in westernized countries are less frequently EBV-associated than cases in other age groups and geographical locales. This study investigated the possibility that polyomaviruses might be involved in the etiology of HL by analysing a series of 35 cases of classical HL using both specific and degenerate PCR assays for polyomavirus genomes. No positive results were obtained, indicating that it is highly unlikely that this virus family is directly involved in the pathogenesis of HL. |
| doi_str_mv | 10.1080/10428190500525789 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_infor</sourceid><recordid>TN_cdi_proquest_miscellaneous_19970055</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>68774043</sourcerecordid><originalsourceid>FETCH-LOGICAL-c435t-260545d8d29b68234959225a59fed99c37077da9bbb12bfac359cd2e42b7fa823</originalsourceid><addsrcrecordid>eNqFkE1PwyAAhonR6Jz-AC-Gk7cqUGiLejHGr2TRgx9XQoFuaFsqtDP797JsiTEm8wQhz_OGPAAcYXSKUYHOMKKkwBwxhBhhecG3wAgjwhNCUbq9vFOSRIDugf0Q3lHEeEZ2wR7OOElZRkbg-c36IZgAZavhvdPTD9vCetF0M9fIc_jooJlbbVploKtg5-pFfJ8vHTg1rWuiGYV-aJyHpXVdsCYcgJ1K1sEcrs8xeL29ebm-TyZPdw_XV5NE0ZT1CckQo0wXmvAyK0hKOeOEMMl4ZTTnKs1RnmvJy7LEpKykShlXmhhKyrySURiDk9Vu593nYEIvGhuUqWvZGjcEkRV5ThFN_wUx53lswyKIV6DyLgRvKtF520i_EBiJZXLxJ3l0jtfjQ9kY_WOsG0fgcgXYtnK-kV_O11r0clE7X3nZKhtEumn_4pc-M7LuZ0p6I97d4NtYeMPvvgG216D8</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>19970055</pqid></control><display><type>article</type><title>Viruses and Hodgkin lymphoma: No evidence of polyomavirus genomes in tumor biopsies</title><source>MEDLINE</source><source>Taylor & Francis Medical Library - CRKN</source><source>Taylor & Francis Journals Complete</source><creator>Wilson, Katherine S. ; Gallagher, Alice ; Freeland, June M. L. ; Shield, Lesley A. ; Jarrett, Ruth F.</creator><creatorcontrib>Wilson, Katherine S. ; Gallagher, Alice ; Freeland, June M. L. ; Shield, Lesley A. ; Jarrett, Ruth F.</creatorcontrib><description>The epidemiology of young adult Hodgkin lymphoma (HL) suggests that delayed exposure to a common childhood pathogen may be involved in disease pathogenesis. The Epstein-Barr virus (EBV) is associated with a proportion of cases but cases of young adult HL in westernized countries are less frequently EBV-associated than cases in other age groups and geographical locales. This study investigated the possibility that polyomaviruses might be involved in the etiology of HL by analysing a series of 35 cases of classical HL using both specific and degenerate PCR assays for polyomavirus genomes. No positive results were obtained, indicating that it is highly unlikely that this virus family is directly involved in the pathogenesis of HL.</description><identifier>ISSN: 1042-8194</identifier><identifier>EISSN: 1029-2403</identifier><identifier>DOI: 10.1080/10428190500525789</identifier><identifier>PMID: 16923562</identifier><language>eng</language><publisher>United States: Informa UK Ltd</publisher><subject>Adult ; Aged ; Biopsy ; degenerate PCR ; DNA Primers - chemistry ; Epstein-Barr virus ; Female ; Genome, Viral ; Herpesvirus 4, Human - genetics ; Hodgkin Disease - pathology ; Hodgkin Disease - virology ; Hodgkin lymphoma ; Humans ; Lymph Nodes - pathology ; Male ; Middle Aged ; Molecular Sequence Data ; Polymerase Chain Reaction ; Polyomavirus ; Polyomavirus - genetics</subject><ispartof>Leukemia & lymphoma, 2006-07, Vol.47 (7), p.1315-1321</ispartof><rights>2006 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 2006</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c435t-260545d8d29b68234959225a59fed99c37077da9bbb12bfac359cd2e42b7fa823</citedby><cites>FETCH-LOGICAL-c435t-260545d8d29b68234959225a59fed99c37077da9bbb12bfac359cd2e42b7fa823</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.1080/10428190500525789$$EPDF$$P50$$Ginformahealthcare$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.1080/10428190500525789$$EHTML$$P50$$Ginformahealthcare$$H</linktohtml><link.rule.ids>314,776,780,27903,27904,59624,59730,60413,60519,61198,61233,61379,61414</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16923562$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wilson, Katherine S.</creatorcontrib><creatorcontrib>Gallagher, Alice</creatorcontrib><creatorcontrib>Freeland, June M. L.</creatorcontrib><creatorcontrib>Shield, Lesley A.</creatorcontrib><creatorcontrib>Jarrett, Ruth F.</creatorcontrib><title>Viruses and Hodgkin lymphoma: No evidence of polyomavirus genomes in tumor biopsies</title><title>Leukemia & lymphoma</title><addtitle>Leuk Lymphoma</addtitle><description>The epidemiology of young adult Hodgkin lymphoma (HL) suggests that delayed exposure to a common childhood pathogen may be involved in disease pathogenesis. The Epstein-Barr virus (EBV) is associated with a proportion of cases but cases of young adult HL in westernized countries are less frequently EBV-associated than cases in other age groups and geographical locales. This study investigated the possibility that polyomaviruses might be involved in the etiology of HL by analysing a series of 35 cases of classical HL using both specific and degenerate PCR assays for polyomavirus genomes. No positive results were obtained, indicating that it is highly unlikely that this virus family is directly involved in the pathogenesis of HL.</description><subject>Adult</subject><subject>Aged</subject><subject>Biopsy</subject><subject>degenerate PCR</subject><subject>DNA Primers - chemistry</subject><subject>Epstein-Barr virus</subject><subject>Female</subject><subject>Genome, Viral</subject><subject>Herpesvirus 4, Human - genetics</subject><subject>Hodgkin Disease - pathology</subject><subject>Hodgkin Disease - virology</subject><subject>Hodgkin lymphoma</subject><subject>Humans</subject><subject>Lymph Nodes - pathology</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Molecular Sequence Data</subject><subject>Polymerase Chain Reaction</subject><subject>Polyomavirus</subject><subject>Polyomavirus - genetics</subject><issn>1042-8194</issn><issn>1029-2403</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1PwyAAhonR6Jz-AC-Gk7cqUGiLejHGr2TRgx9XQoFuaFsqtDP797JsiTEm8wQhz_OGPAAcYXSKUYHOMKKkwBwxhBhhecG3wAgjwhNCUbq9vFOSRIDugf0Q3lHEeEZ2wR7OOElZRkbg-c36IZgAZavhvdPTD9vCetF0M9fIc_jooJlbbVploKtg5-pFfJ8vHTg1rWuiGYV-aJyHpXVdsCYcgJ1K1sEcrs8xeL29ebm-TyZPdw_XV5NE0ZT1CckQo0wXmvAyK0hKOeOEMMl4ZTTnKs1RnmvJy7LEpKykShlXmhhKyrySURiDk9Vu593nYEIvGhuUqWvZGjcEkRV5ThFN_wUx53lswyKIV6DyLgRvKtF520i_EBiJZXLxJ3l0jtfjQ9kY_WOsG0fgcgXYtnK-kV_O11r0clE7X3nZKhtEumn_4pc-M7LuZ0p6I97d4NtYeMPvvgG216D8</recordid><startdate>20060701</startdate><enddate>20060701</enddate><creator>Wilson, Katherine S.</creator><creator>Gallagher, Alice</creator><creator>Freeland, June M. L.</creator><creator>Shield, Lesley A.</creator><creator>Jarrett, Ruth F.</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7U9</scope><scope>8FD</scope><scope>FR3</scope><scope>H94</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>20060701</creationdate><title>Viruses and Hodgkin lymphoma: No evidence of polyomavirus genomes in tumor biopsies</title><author>Wilson, Katherine S. ; Gallagher, Alice ; Freeland, June M. L. ; Shield, Lesley A. ; Jarrett, Ruth F.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c435t-260545d8d29b68234959225a59fed99c37077da9bbb12bfac359cd2e42b7fa823</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Biopsy</topic><topic>degenerate PCR</topic><topic>DNA Primers - chemistry</topic><topic>Epstein-Barr virus</topic><topic>Female</topic><topic>Genome, Viral</topic><topic>Herpesvirus 4, Human - genetics</topic><topic>Hodgkin Disease - pathology</topic><topic>Hodgkin Disease - virology</topic><topic>Hodgkin lymphoma</topic><topic>Humans</topic><topic>Lymph Nodes - pathology</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Molecular Sequence Data</topic><topic>Polymerase Chain Reaction</topic><topic>Polyomavirus</topic><topic>Polyomavirus - genetics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wilson, Katherine S.</creatorcontrib><creatorcontrib>Gallagher, Alice</creatorcontrib><creatorcontrib>Freeland, June M. L.</creatorcontrib><creatorcontrib>Shield, Lesley A.</creatorcontrib><creatorcontrib>Jarrett, Ruth F.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Leukemia & lymphoma</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wilson, Katherine S.</au><au>Gallagher, Alice</au><au>Freeland, June M. L.</au><au>Shield, Lesley A.</au><au>Jarrett, Ruth F.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Viruses and Hodgkin lymphoma: No evidence of polyomavirus genomes in tumor biopsies</atitle><jtitle>Leukemia & lymphoma</jtitle><addtitle>Leuk Lymphoma</addtitle><date>2006-07-01</date><risdate>2006</risdate><volume>47</volume><issue>7</issue><spage>1315</spage><epage>1321</epage><pages>1315-1321</pages><issn>1042-8194</issn><eissn>1029-2403</eissn><abstract>The epidemiology of young adult Hodgkin lymphoma (HL) suggests that delayed exposure to a common childhood pathogen may be involved in disease pathogenesis. The Epstein-Barr virus (EBV) is associated with a proportion of cases but cases of young adult HL in westernized countries are less frequently EBV-associated than cases in other age groups and geographical locales. This study investigated the possibility that polyomaviruses might be involved in the etiology of HL by analysing a series of 35 cases of classical HL using both specific and degenerate PCR assays for polyomavirus genomes. No positive results were obtained, indicating that it is highly unlikely that this virus family is directly involved in the pathogenesis of HL.</abstract><cop>United States</cop><pub>Informa UK Ltd</pub><pmid>16923562</pmid><doi>10.1080/10428190500525789</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1042-8194 |
| ispartof | Leukemia & lymphoma, 2006-07, Vol.47 (7), p.1315-1321 |
| issn | 1042-8194 1029-2403 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_19970055 |
| source | MEDLINE; Taylor & Francis Medical Library - CRKN; Taylor & Francis Journals Complete |
| subjects | Adult Aged Biopsy degenerate PCR DNA Primers - chemistry Epstein-Barr virus Female Genome, Viral Herpesvirus 4, Human - genetics Hodgkin Disease - pathology Hodgkin Disease - virology Hodgkin lymphoma Humans Lymph Nodes - pathology Male Middle Aged Molecular Sequence Data Polymerase Chain Reaction Polyomavirus Polyomavirus - genetics |
| title | Viruses and Hodgkin lymphoma: No evidence of polyomavirus genomes in tumor biopsies |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-22T13%3A49%3A59IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_infor&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Viruses%20and%20Hodgkin%20lymphoma:%20No%20evidence%20of%20polyomavirus%20genomes%20in%20tumor%20biopsies&rft.jtitle=Leukemia%20&%20lymphoma&rft.au=Wilson,%20Katherine%20S.&rft.date=2006-07-01&rft.volume=47&rft.issue=7&rft.spage=1315&rft.epage=1321&rft.pages=1315-1321&rft.issn=1042-8194&rft.eissn=1029-2403&rft_id=info:doi/10.1080/10428190500525789&rft_dat=%3Cproquest_infor%3E68774043%3C/proquest_infor%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=19970055&rft_id=info:pmid/16923562&rfr_iscdi=true |