Progressive reduction in poly-ADP-ribosylation of histone proteins during Dalton's lymphoma induced ascites tumorigenesis in mice

Poly-ADP-ribosylation (PAR) reaction, which primarily modifies histone proteins, is postulated to have decisive influence in carcinogenesis. Therefore, it has been suggested as a biomarker of carcinogenesis. Dalton's lymphoma induced ascites tumorigenesis in mice provides a convenient model to...

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Veröffentlicht in:	Cancer letters 2006-07, Vol.238 (1), p.135-141
Hauptverfasser:	Jaylata Devi, B., Sharan, R.N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdomen ADP-Ribosylation Factors - metabolism Animals Ascites - metabolism Ascites - pathology Ascites tumorigenesis Biomarkers, Tumor - analysis Biomarkers, Tumor - metabolism Blood Cancer Chromatin Dalton's Lymphoma (DL) Disease Models, Animal Disease Progression Down-Regulation Drinking water Hepatocytes - pathology Histone proteins Histones - analysis Histones - metabolism Immunoprobe assay In vivo Lymphoma - metabolism Lymphoma - pathology Mice Molecular weight Poly Adenosine Diphosphate Ribose - metabolism Poly-ADP-ribosylation (PAR) Polyclonal antibodies Proteins Spleen Spleen - cytology Spleen - pathology Tumorigenesis Western blot
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