Folate deficiency and ionizing radiation cause DNA breaks in primary human lymphocytes: a comparison

ABSTRACT DNA double‐strand breaks, the most serious DNA lesion caused by ionizing radiation, are also caused by several vitamin or mineral deficiencies, such as for folate. Primary human lymphocytes were either irradiated or cultured at different levels of folate deficiency to assess cell proliferat...

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Veröffentlicht in:	The FASEB journal 2004-01, Vol.18 (1), p.209-211
Hauptverfasser:	Courtemanche, Chantal, Huang, Arnold C., Elson‐Schwab, Ilan, Kerry, Nicole, Ng, Bernice Y., Ames, Bruce N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis cancer risk Cell Cycle - radiation effects Cell Division - radiation effects Cells, Cultured Comet Assay DNA Damage Folic Acid - physiology Gene Expression Profiling Humans ionizing radiation Lymphocytes - cytology Lymphocytes - metabolism Lymphocytes - radiation effects microarray nutrition Radiation Dosage Radiation, Ionizing
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