Epigenetic silencing of E- and N-cadherins in the stroma of mouse thymic lymphomas

Aberrant expression of some tumour suppressor genes and oncogenes by thymocytes had been involved in the development of primary thymic lymphomas induced by γ-irradiation, but genetic alterations affecting critical genes expressed by stromal cells have not been yet explored. This paper analyzes a ser...

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Veröffentlicht in:	Carcinogenesis (New York) 2006-05, Vol.27 (5), p.1081-1089
Hauptverfasser:	de Yzaguirre, M.Matabuena, Hernández, J.Santos, Navarro, P.Fernández, Nieva, P.López, Herranz, M., Fraga, M.F., Esteller, M., Juarranz, A., Fernández-Piqueras, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Biological and medical sciences Cadherins - genetics Carcinogenesis, carcinogens and anticarcinogens Epigenesis, Genetic Gene Silencing Hematologic and hematopoietic diseases Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphoma - genetics Lymphoma - pathology Medical sciences Mice Mice, Inbred BALB C Mice, Inbred C57BL Molecular Sequence Data Neoplasms, Radiation-Induced - genetics Sequence Analysis, DNA Stromal Cells - cytology Thymus Neoplasms - genetics Tumors
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