Age-related thymic activity in adults following chemotherapy-induced lymphopenia

Background The potential role of the adult thymus in T‐cell homeostasis subsequent to lymphopenia remains the subject of debate. We examined whether thymic activity contributes to reconstitution of the peripheral T‐cell pool, a critical process for patients recovering from antineoplastic therapy. M...

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Veröffentlicht in:	European journal of clinical investigation 2005-06, Vol.35 (6), p.380-387
Hauptverfasser:	Sfikakis, P. P., Gourgoulis, G. M., Moulopoulos, L. A., Kouvatseas, G., Theofilopoulos, A. N., Dimopoulos, M. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aging Aging - physiology Antineoplastic Agents - adverse effects Biological and medical sciences CD4-Positive T-Lymphocytes - physiology Female General aspects Hematologic and hematopoietic diseases Humans immune senescence Leukocyte Common Antigens - analysis Leukocyte Common Antigens - biosynthesis Lymphatic Diseases - pathology lymphopenia Lymphopenia - chemically induced Male Medical sciences Middle Aged Neoplasms - drug therapy Other diseases. Hematologic involvement in other diseases T-cell thymus Thymus Gland - drug effects Thymus Gland - pathology Thymus Gland - physiology
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