Imprinting Status in Two Human Parthenogenetic Embryonic Stem Cell Lines: Analysis of 63 Imprinted Gene Expression Levels in Undifferentiated and Early Differentiated Stages

Human parthenogenetic embryonic stem cells (hPESCs) represent a source of histocompatible tissues for transplantation and carry two copies of the maternal genome, but lack the paternal genome. In this study, we selected 63 known human imprinted genes to investigate the imprinting status of hPESC. Th...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Stem cells and development 2018-03, Vol.27 (6), p.43-439
Hauptverfasser:	Mai, Qingyun, Mai, Xiuyun, Huang, Xin, Zhang, Dan, Huang, Kejun, Zhou, Canquan
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Differentiation - genetics Cell Line DNA Methylation - genetics Down-Regulation - genetics Embryonic Stem Cells - physiology Gene Expression - genetics Gene Expression Regulation, Developmental - genetics Genomic Imprinting - genetics Humans Original Research Reports Parthenogenesis - genetics Up-Regulation - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!