Effects of Copper and Zinc Supplementation on Weight Gain and Hematological Parameters in Pre-weaning Calves
Cow-calf operations may be affected by trace mineral deficiencies, particularly copper (Cu) and zinc (Zn) deficiency, which may decrease the calf daily weight gain and alter hematological parameters. We evaluated the effect of Cu and Zn supplementation on pre-weaning calves ( n = 40; 92 ± 6 kg init...
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| Veröffentlicht in: | Biological trace element research 2018-10, Vol.185 (2), p.327-331 |
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| creator | Mattioli, Guillermo Alberto Rosa, Diana Esther Turic, Esteban Relling, Alejandro Enrique Galarza, Esteban Fazzio, Luis Emilio |
| description | Cow-calf operations may be affected by trace mineral deficiencies, particularly copper (Cu) and zinc (Zn) deficiency, which may decrease the calf daily weight gain and alter hematological parameters. We evaluated the effect of Cu and Zn supplementation on pre-weaning calves (
n
= 40; 92 ± 6 kg initial body weight) from the Salado River basin, Buenos Aires, Argentina. Calves were divided into four groups (
n
= 10 each) and subcutaneously administered 0.3 mg/kg Cu (Cu group), 1 mg/kg Zn (Zn group), Cu and Zn together (Cu + Zn group), and sterile saline solution (control group) every 40 days for 120 days. Plasma Cu and Zn concentrations, hematological parameters, and weight were recorded every 40 days. A completely randomized 2 × 2 factorial treatment design was used and data were analyzed with a mixed model for repeated measures over time. Cu and Zn were detected in plasma after the second sampling. Cu × Zn interaction was significant (
p
= 0.09), being Cu concentration higher in the Cu + Zn than in the Cu group. Differences in weight gain (Zn × time interaction;
p
0.1). On the other hand, none of the treatments altered any of the hematological parameters assessed (
p
> 0.1). Our results show the risk of lower weight gain due to Zn deficiency in pre-weaning calves raised in the Salado River basin. |
| doi_str_mv | 10.1007/s12011-017-1239-0 |
| format | Article |
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n
= 40; 92 ± 6 kg initial body weight) from the Salado River basin, Buenos Aires, Argentina. Calves were divided into four groups (
n
= 10 each) and subcutaneously administered 0.3 mg/kg Cu (Cu group), 1 mg/kg Zn (Zn group), Cu and Zn together (Cu + Zn group), and sterile saline solution (control group) every 40 days for 120 days. Plasma Cu and Zn concentrations, hematological parameters, and weight were recorded every 40 days. A completely randomized 2 × 2 factorial treatment design was used and data were analyzed with a mixed model for repeated measures over time. Cu and Zn were detected in plasma after the second sampling. Cu × Zn interaction was significant (
p
= 0.09), being Cu concentration higher in the Cu + Zn than in the Cu group. Differences in weight gain (Zn × time interaction;
p
< 0.01) were observed in the Zn but not in the Cu group (
p
> 0.1). On the other hand, none of the treatments altered any of the hematological parameters assessed (
p
> 0.1). Our results show the risk of lower weight gain due to Zn deficiency in pre-weaning calves raised in the Salado River basin.</description><identifier>ISSN: 0163-4984</identifier><identifier>EISSN: 1559-0720</identifier><identifier>DOI: 10.1007/s12011-017-1239-0</identifier><identifier>PMID: 29404982</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Animals ; Biochemistry ; Biomedical and Life Sciences ; Biotechnology ; Body weight ; Body weight gain ; Calves ; Cattle ; Copper ; Copper - administration & dosage ; Copper - blood ; Copper - pharmacology ; Data processing ; Dietary Supplements ; Fish ; Hematology ; Life Sciences ; Nutrient deficiency ; Nutrition ; Oncology ; Parameters ; River basins ; Rivers ; Supplements ; Weaning ; Weight gain ; Weight Gain - drug effects ; Zinc ; Zinc - administration & dosage ; Zinc - blood ; Zinc - pharmacology</subject><ispartof>Biological trace element research, 2018-10, Vol.185 (2), p.327-331</ispartof><rights>Springer Science+Business Media, LLC, part of Springer Nature 2018</rights><rights>Biological Trace Element Research is a copyright of Springer, (2018). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c372t-5175b4746957fb1adb8ce51b5f66fdc9b3be99cd9b7c104b2c603dfdbb171d73</citedby><cites>FETCH-LOGICAL-c372t-5175b4746957fb1adb8ce51b5f66fdc9b3be99cd9b7c104b2c603dfdbb171d73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s12011-017-1239-0$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s12011-017-1239-0$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29404982$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mattioli, Guillermo Alberto</creatorcontrib><creatorcontrib>Rosa, Diana Esther</creatorcontrib><creatorcontrib>Turic, Esteban</creatorcontrib><creatorcontrib>Relling, Alejandro Enrique</creatorcontrib><creatorcontrib>Galarza, Esteban</creatorcontrib><creatorcontrib>Fazzio, Luis Emilio</creatorcontrib><title>Effects of Copper and Zinc Supplementation on Weight Gain and Hematological Parameters in Pre-weaning Calves</title><title>Biological trace element research</title><addtitle>Biol Trace Elem Res</addtitle><addtitle>Biol Trace Elem Res</addtitle><description>Cow-calf operations may be affected by trace mineral deficiencies, particularly copper (Cu) and zinc (Zn) deficiency, which may decrease the calf daily weight gain and alter hematological parameters. We evaluated the effect of Cu and Zn supplementation on pre-weaning calves (
n
= 40; 92 ± 6 kg initial body weight) from the Salado River basin, Buenos Aires, Argentina. Calves were divided into four groups (
n
= 10 each) and subcutaneously administered 0.3 mg/kg Cu (Cu group), 1 mg/kg Zn (Zn group), Cu and Zn together (Cu + Zn group), and sterile saline solution (control group) every 40 days for 120 days. Plasma Cu and Zn concentrations, hematological parameters, and weight were recorded every 40 days. A completely randomized 2 × 2 factorial treatment design was used and data were analyzed with a mixed model for repeated measures over time. Cu and Zn were detected in plasma after the second sampling. Cu × Zn interaction was significant (
p
= 0.09), being Cu concentration higher in the Cu + Zn than in the Cu group. Differences in weight gain (Zn × time interaction;
p
< 0.01) were observed in the Zn but not in the Cu group (
p
> 0.1). On the other hand, none of the treatments altered any of the hematological parameters assessed (
p
> 0.1). Our results show the risk of lower weight gain due to Zn deficiency in pre-weaning calves raised in the Salado River basin.</description><subject>Animals</subject><subject>Biochemistry</subject><subject>Biomedical and Life Sciences</subject><subject>Biotechnology</subject><subject>Body weight</subject><subject>Body weight gain</subject><subject>Calves</subject><subject>Cattle</subject><subject>Copper</subject><subject>Copper - administration & dosage</subject><subject>Copper - blood</subject><subject>Copper - pharmacology</subject><subject>Data processing</subject><subject>Dietary Supplements</subject><subject>Fish</subject><subject>Hematology</subject><subject>Life Sciences</subject><subject>Nutrient deficiency</subject><subject>Nutrition</subject><subject>Oncology</subject><subject>Parameters</subject><subject>River basins</subject><subject>Rivers</subject><subject>Supplements</subject><subject>Weaning</subject><subject>Weight gain</subject><subject>Weight Gain - drug effects</subject><subject>Zinc</subject><subject>Zinc - 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administration & dosage</topic><topic>Copper - blood</topic><topic>Copper - pharmacology</topic><topic>Data processing</topic><topic>Dietary Supplements</topic><topic>Fish</topic><topic>Hematology</topic><topic>Life Sciences</topic><topic>Nutrient deficiency</topic><topic>Nutrition</topic><topic>Oncology</topic><topic>Parameters</topic><topic>River basins</topic><topic>Rivers</topic><topic>Supplements</topic><topic>Weaning</topic><topic>Weight gain</topic><topic>Weight Gain - drug effects</topic><topic>Zinc</topic><topic>Zinc - administration & dosage</topic><topic>Zinc - blood</topic><topic>Zinc - pharmacology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mattioli, Guillermo Alberto</creatorcontrib><creatorcontrib>Rosa, Diana Esther</creatorcontrib><creatorcontrib>Turic, Esteban</creatorcontrib><creatorcontrib>Relling, Alejandro Enrique</creatorcontrib><creatorcontrib>Galarza, Esteban</creatorcontrib><creatorcontrib>Fazzio, Luis Emilio</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Aqualine</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Oceanic Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Water Resources Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Earth, Atmospheric & Aquatic Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 3: Aquatic Pollution & Environmental Quality</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Earth, Atmospheric & Aquatic Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Biological trace element research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mattioli, Guillermo Alberto</au><au>Rosa, Diana Esther</au><au>Turic, Esteban</au><au>Relling, Alejandro Enrique</au><au>Galarza, Esteban</au><au>Fazzio, Luis Emilio</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of Copper and Zinc Supplementation on Weight Gain and Hematological Parameters in Pre-weaning Calves</atitle><jtitle>Biological trace element research</jtitle><stitle>Biol Trace Elem Res</stitle><addtitle>Biol Trace Elem Res</addtitle><date>2018-10-01</date><risdate>2018</risdate><volume>185</volume><issue>2</issue><spage>327</spage><epage>331</epage><pages>327-331</pages><issn>0163-4984</issn><eissn>1559-0720</eissn><abstract>Cow-calf operations may be affected by trace mineral deficiencies, particularly copper (Cu) and zinc (Zn) deficiency, which may decrease the calf daily weight gain and alter hematological parameters. We evaluated the effect of Cu and Zn supplementation on pre-weaning calves (
n
= 40; 92 ± 6 kg initial body weight) from the Salado River basin, Buenos Aires, Argentina. Calves were divided into four groups (
n
= 10 each) and subcutaneously administered 0.3 mg/kg Cu (Cu group), 1 mg/kg Zn (Zn group), Cu and Zn together (Cu + Zn group), and sterile saline solution (control group) every 40 days for 120 days. Plasma Cu and Zn concentrations, hematological parameters, and weight were recorded every 40 days. A completely randomized 2 × 2 factorial treatment design was used and data were analyzed with a mixed model for repeated measures over time. Cu and Zn were detected in plasma after the second sampling. Cu × Zn interaction was significant (
p
= 0.09), being Cu concentration higher in the Cu + Zn than in the Cu group. Differences in weight gain (Zn × time interaction;
p
< 0.01) were observed in the Zn but not in the Cu group (
p
> 0.1). On the other hand, none of the treatments altered any of the hematological parameters assessed (
p
> 0.1). Our results show the risk of lower weight gain due to Zn deficiency in pre-weaning calves raised in the Salado River basin.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>29404982</pmid><doi>10.1007/s12011-017-1239-0</doi><tpages>5</tpages></addata></record> |
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| subjects | Animals Biochemistry Biomedical and Life Sciences Biotechnology Body weight Body weight gain Calves Cattle Copper Copper - administration & dosage Copper - blood Copper - pharmacology Data processing Dietary Supplements Fish Hematology Life Sciences Nutrient deficiency Nutrition Oncology Parameters River basins Rivers Supplements Weaning Weight gain Weight Gain - drug effects Zinc Zinc - administration & dosage Zinc - blood Zinc - pharmacology |
| title | Effects of Copper and Zinc Supplementation on Weight Gain and Hematological Parameters in Pre-weaning Calves |
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