Induction of Neutralizing Antibodies and Th1-Polarized and CD4-Independent CD8 super(+) T-Cell Responses following Delivery of Human Immunodeficiency Virus Type 1 Tat Protein by Recombinant Adenylate Cyclase of Bordetella pertussis

HIV-Tat, a conserved protein playing a key role in the early life cycle of the human immunodeficiency virus (HIV) has been proposed as a potential AIDS vaccine. An HIV-Tat-based vaccine should elicit a broad, long-lasting, and neutralizing immune response. We have previously demonstrated that the ad...

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Veröffentlicht in:	Journal of virology 2005-08, Vol.79 (15), p.9872-9884
Hauptverfasser:	Mascarell, Laurent, Fayolle, Catherine, Bauche, Cecile, Ladant, Daniel, Leclerc, Claude
Format:	Artikel
Sprache:	eng
Schlagworte:	Bordetella pertussis Human immunodeficiency virus 1
Online-Zugang:	Volltext
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