Clusterin promotes growth and invasion of clear cell renal carcinoma cell by upregulation of S100A4 expression

Clusterin promotes cell proliferation, motility and invasiveness in human renal cell carcinoma (RCC) cells but the underlying molecular mechanisms of this action are largely unknown. The aim of this study was to investigate the effects of clusterin on cancer cell growth, invasion and S100A4 expressi...

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Veröffentlicht in:	Cancer biomarkers : section A of Disease markers 2018-01, Vol.21 (4), p.915-923
Hauptverfasser:	Liu, Yuan, Men, Changping, Xu, Yingmin, Zhao, Kai, Luo, Lei, Dong, Dahai, Yu, Qinchao
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal tissues Assaying Cancer Cell growth Cell migration Cell proliferation Clear cell-type renal cell carcinoma Clusterin Complementary DNA Gene expression Immunohistochemistry In vivo methods and tests Invasiveness Kidney cancer Molecular modelling Reverse transcription Ribonucleic acid RNA S100A4 protein Signal transduction siRNA Tumors Up-regulation Xenografts Xenotransplantation
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