Infant botulism in the age of botulism immune globulin
Infant botulism causes acute bulbar dysfunction, weakness, and respiratory failure in infants living in endemic regions of the United States. Until Food and Drug Administration approval of botulism immune globulin (BIG) in October 2003, management of infant botulism had changed little since the 1970...
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| Veröffentlicht in: | Neurology 2005-06, Vol.64 (12), p.2029-2032 |
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| container_issue | 12 |
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| container_title | Neurology |
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| creator | Thompson, J A Filloux, F M Van Orman, C B Swoboda, K Peterson, P Firth, S D Bale, Jr, J F |
| description | Infant botulism causes acute bulbar dysfunction, weakness, and respiratory failure in infants living in endemic regions of the United States. Until Food and Drug Administration approval of botulism immune globulin (BIG) in October 2003, management of infant botulism had changed little since the 1970s. Currently, IV therapy with BIG is advised to shorten the duration and diminish the potential complications of the disorder. This review describes two decades of experience with infant botulism and provides a contemporary perspective on the role and benefit of BIG. |
| doi_str_mv | 10.1212/01.WNL.0000166950.35189.5E |
| format | Article |
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Until Food and Drug Administration approval of botulism immune globulin (BIG) in October 2003, management of infant botulism had changed little since the 1970s. Currently, IV therapy with BIG is advised to shorten the duration and diminish the potential complications of the disorder. 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| ispartof | Neurology, 2005-06, Vol.64 (12), p.2029-2032 |
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| language | eng |
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| source | MEDLINE; Journals@Ovid Complete; Alma/SFX Local Collection |
| subjects | Botulism - drug therapy Botulism - epidemiology Botulism - physiopathology Clostridium botulinum Environmental Exposure - statistics & numerical data Feeding Methods - statistics & numerical data Female Gastrointestinal Tract - microbiology Gastrointestinal Tract - physiopathology Hospitalization - statistics & numerical data Humans Immunoglobulins - therapeutic use Immunoglobulins, Intravenous - therapeutic use Infant Length of Stay Male United States - epidemiology |
| title | Infant botulism in the age of botulism immune globulin |
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