Acute treatment with the PPAR gamma agonist pioglitazone and ibuprofen reduces glial inflammation and A beta 1-42 levels in APPV717I transgenic mice

Neuritic plaques in the brain of Alzheimer's disease patients are characterized by beta -amyloid deposits associated with a glia-mediated inflammatory response. Non-steroidal anti-inflammatory drug (NSAID) therapy reduces Alzheimer's disease risk and ameliorates microglial reactivity in Al...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Brain (London, England : 1878) England : 1878), 2005-06, Vol.128 (6), p.1442-1453
Hauptverfasser:	Heneka, Michael T, Sastre, Magdalena, Dumitrescu-Ozimek, Lucia, Hanke, Anne, Dewachter, Ilse, Kuiperi, Cuno, O'Banion, Kerry, Klockgether, Thomas, Van Leuven, Fred, Landreth, Gary E
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!