Effect of systemic administration of lipopolysaccharides derived from Porphyromonas gingivalis on gene expression in mice kidney

Although an association between periodontitis and chronic kidney disease (CKD) has been suggested, the mechanism involved remains unclear. Herein, we examined the global gene expression profile in a mouse model that showed no acute inflammation in the kidney following stimulation with lipopolysaccha...

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Veröffentlicht in:	Medical molecular morphology 2018-09, Vol.51 (3), p.156-165
Hauptverfasser:	Harada, Fumiya, Uehara, Osamu, Morikawa, Tetsuro, Hiraki, Daichi, Onishi, Aya, Toraya, Seiko, Adhikari, Bhoj Raj, Takai, Rie, Yoshida, Koki, Sato, Jun, Nishimura, Michiko, Chiba, Itsuo, Wu, Ching Zong, Abiko, Yoshihiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Anatomy Animals Cells, Cultured Cytokines - immunology Cytokines - metabolism Disease Models, Animal DNA microarrays Endothelial cells Endothelial Cells - immunology Endothelial Cells - metabolism Gene expression Gene Expression Profiling Gum disease Humans Kidney - immunology Kidney - pathology Kidney diseases Lipopolysaccharides Lipopolysaccharides - immunology Male Medicine Medicine & Public Health Mice Mice, Inbred C57BL Molecular Medicine Oligonucleotide Array Sequence Analysis Original Paper Pathology Periodontitis Periodontitis - complications Periodontitis - microbiology Periodontitis - pathology Polymerase chain reaction Porphyromonas gingivalis Porphyromonas gingivalis - metabolism Primary Cell Culture Renal Insufficiency, Chronic - etiology Renal Insufficiency, Chronic - pathology RNA, Messenger - metabolism Rodents Up-Regulation
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