Increased mitochondrial turnover in the skeletal muscle of fasted, castrated mice is related to the magnitude of autophagy activation and muscle atrophy

Androgen-deficiency promotes muscle atrophy in part by increasing autophagy-mediated muscle protein breakdown during the fasted state, but factors contributing to this remain undefined. To identify novel factors, mice were subjected to sham or castration surgery. Seven-weeks post-surgery, mice were...

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Veröffentlicht in:	Molecular and cellular endocrinology 2018-09, Vol.473, p.178-185
Hauptverfasser:	Rossetti, Michael L., Steiner, Jennifer L., Gordon, Bradley S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Hypogonadism Mitochondrial dysfunction Mitophagy Testosterone
Online-Zugang:	Volltext
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