Stachydrine ameliorates carbon tetrachloride-induced hepatic fibrosis by inhibiting inflammation, oxidative stress and regulating MMPs/TIMPs system in rats

Inflammation and oxidative stress are two crucial factors mediating liver fibrosis. Stachydrine (STA) is a naturally occurring compound extracted from a medicinal plant Leonuru heterophyllus, which can inhibit the proliferation and induce the apoptosis of breast cancer cells, relieve high glucose-in...

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Veröffentlicht in:	Biomedicine & pharmacotherapy 2018-01, Vol.97, p.1586-1594
Hauptverfasser:	Zhang, Jinlin, Yang, Aihua, Wu, Yu, Guan, Wei, Xiong, Biao, Peng, Xiaoqing, Wei, Xiaojin, Chen, Chang, Liu, Zhaoguo
Format:	Artikel
Sprache:	eng
Schlagworte:	Inflammation Liver fibrosis Matrix metalloproteinase Oxidative stress Stachydrine
Online-Zugang:	Volltext
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