Transfer RNA modification and infection – Implications for pathogenicity and host responses

Transfer RNA (tRNA) molecules are sumptuously decorated with evolutionary conserved post-transcriptional nucleoside modifications that are essential for structural stability and ensure efficient protein translation. The tRNA modification levels change significantly in response to physiological stres...

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Veröffentlicht in:	Biochimica et biophysica acta. Gene regulatory mechanisms 2018-04, Vol.1861 (4), p.419-432
Hauptverfasser:	Koh, Cha San, Sarin, L. Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptation, Physiological - genetics Animals Anticodon - genetics Codon - genetics Genetic Code Host-pathogen interaction Host-Pathogen Interactions - genetics Humans Infection Infection - genetics Infection - physiopathology Metabolic Networks and Pathways - physiology Models, Molecular Nucleic Acid Conformation Oxidative Stress - genetics Post-translational modification Protein Biosynthesis Ribosomes - metabolism RNA Processing, Post-Transcriptional RNA Stability RNA, Transfer - chemistry RNA, Transfer - genetics RNA, Transfer - metabolism RNA-Directed DNA Polymerase - metabolism Stress Stress, Physiological - genetics Sulfur - metabolism Transfer RNA Virulence - genetics
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