Dysregulated Expression of RPS4Y1 (Ribosomal Protein S4, Y-Linked 1) Impairs STAT3 (Signal Transducer and Activator of Transcription 3) Signaling to Suppress Trophoblast Cell Migration and Invasion in Preeclampsia

Normal placentation and a successful pregnancy depend on appropriate trophoblast cell migration and invasion. Inadequate trophoblast invasion and impaired spiral artery remodeling may lead to pregnancy-related disorders, such as preeclampsia. RPS4Y1 (ribosomal protein S4, Y-linked 1) is a member of...

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Veröffentlicht in:	Hypertension (Dallas, Tex. 1979) Tex. 1979), 2018-03, Vol.71 (3), p.481-490
Hauptverfasser:	Chen, Xuehai, Tong, Chao, Li, Haiying, Peng, Wei, Li, Rong, Luo, Xin, Ge, Huisheng, Ran, Yuxin, Li, Qin, Liu, Yamin, Xiong, Xi, Bai, Yuxiang, Zhang, Hua, Baker, Philip N, Liu, Xiru, Qi, Hongbo
Format:	Artikel
Sprache:	eng
Schlagworte:	Abortion, Legal Adult Cell Movement - genetics Cohort Studies Female Gene Expression Regulation Humans Phosphorylation - genetics Placenta - pathology Pre-Eclampsia - genetics Predictive Value of Tests Pregnancy Pregnancy Trimester, First Prospective Studies Ribosomal Proteins - genetics Sensitivity and Specificity Signal Transduction - genetics STAT3 Transcription Factor - genetics Trophoblasts - pathology Up-Regulation
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