Scalable production of core-shell nanoparticles by flash nanocomplexation to enhance mucosal transport for oral delivery of insulin

Scalable manufacturing continues to present a major barrier for clinical translation of nanotherapeutics. Methods available for fabricating protein-encapsulating nanoparticles in a scalable fashion are scarce. Protein delivery often requires multiple functionalities to be incorporated into the same...

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Veröffentlicht in:Nanoscale 2018-02, Vol.10 (7), p.3307-3319
Hauptverfasser: He, Zhiyu, Liu, Zhijia, Tian, Houkuan, Hu, Yizong, Liu, Lixin, Leong, Kam W, Mao, Hai-Quan, Chen, Yongming
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Sprache:eng
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