Proliferation of Pulmonary Interstitial Fibroblasts Is Mediated by Transforming Growth Factor- beta 1-induced Release of Extracellular Fibroblast Growth Factor-2 and Phosphorylation of p38 MAPK and JNK

Idiopathic pulmonary fibrosis (IPF; a progressive lung disease) is characterized by parenchymal remodeling with enlarged air spaces called honeycomb cysts and palisades of fibroblasts called fibroblast foci. In IPF, lung epithelial cells covering honeycomb cysts and fibroblast foci aberrantly expres...

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Veröffentlicht in:	The Journal of biological chemistry 2005-12, Vol.280 (52), p.43000-43009
Hauptverfasser:	Khalil, Nasreen, Xu, Ying Dong, O'Connor, Robert, Duronio, Vincent
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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