Botulinum toxin type A improves blood flow in vascular thoracic outlet syndrome
A 28-yr-old man, diagnosed with vascular thoracic outlet syndrome, had his right anterior scalene muscle injected with botulinum toxin type A under ultrasound guidance. Subclavian artery flow rates were measured with Doppler ultrasound before and 3 wks after the injection. At 3 wks, symptoms had imp...
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Veröffentlicht in: | American journal of physical medicine & rehabilitation 2008-11, Vol.87 (11), p.956-959 |
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description | A 28-yr-old man, diagnosed with vascular thoracic outlet syndrome, had his right anterior scalene muscle injected with botulinum toxin type A under ultrasound guidance. Subclavian artery flow rates were measured with Doppler ultrasound before and 3 wks after the injection. At 3 wks, symptoms had improved. The reduction in subclavian artery flow rate associated with the arm abducted to the side with 90-degree external rotation decreased from 132.8 to 87.7 cm/sec preinjection compared with a smaller decrease postinjection from 132.8 to 119.1 cm/sec. An improved subclavian artery flow was seen after scalene muscle chemodenervation for vascular thoracic outlet syndrome. This suggests its potential as a diagnostic test, treatment option, and predictor for surgical intervention. |
doi_str_mv | 10.1097/PHM.0b013e31818a51c3 |
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Subclavian artery flow rates were measured with Doppler ultrasound before and 3 wks after the injection. At 3 wks, symptoms had improved. The reduction in subclavian artery flow rate associated with the arm abducted to the side with 90-degree external rotation decreased from 132.8 to 87.7 cm/sec preinjection compared with a smaller decrease postinjection from 132.8 to 119.1 cm/sec. An improved subclavian artery flow was seen after scalene muscle chemodenervation for vascular thoracic outlet syndrome. 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This suggests its potential as a diagnostic test, treatment option, and predictor for surgical intervention.</description><subject>Adult</subject><subject>Botulinum Toxins, Type A - administration & dosage</subject><subject>Humans</subject><subject>Injections, Intramuscular</subject><subject>Male</subject><subject>Neck Muscles - drug effects</subject><subject>Neuromuscular Agents - therapeutic use</subject><subject>Regional Blood Flow - drug effects</subject><subject>Subclavian Artery - physiopathology</subject><subject>Thoracic Outlet Syndrome - drug therapy</subject><issn>0894-9115</issn><issn>1537-7385</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkE9LwzAYxoMobk6_gUhO3qp5m2ZJjnOoEybzoOeSpG-xki6zSaf79lY2EHwu7-H5w8uPkEtgN8C0vH1ZPN8wy4AjBwXKCHD8iIxBcJlJrsQxGTOli0wDiBE5i_GDMSY0l6dkBErzqRB6TFZ3IfW-WfctTeG7WdO02yCd0abddGGLkVofQkVrH77o4G5NdL03HU3voTOucTT0yWOicbeuutDiOTmpjY94cbgT8vZw_zpfZMvV49N8tswc59OU5ZhLlNJoBgYHWe6MtQoKqTWzytq8kogKDK-VsVwAGjUFW9Wy0oUqNJ-Q6_3u8OZnjzGVbRMdem_WGPpYgta5YDkMwWIfdF2IscO63HRNa7pdCaz8BVkOIMv_IIfa1WG_ty1Wf6UDOf4DujBxmA</recordid><startdate>200811</startdate><enddate>200811</enddate><creator>Danielson, Kirk</creator><creator>Odderson, Ib R</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T7</scope><scope>7U7</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>P64</scope></search><sort><creationdate>200811</creationdate><title>Botulinum toxin type A improves blood flow in vascular thoracic outlet syndrome</title><author>Danielson, Kirk ; Odderson, Ib R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c336t-2e27e77a901aeeeeb3cabb8147990b8bb2d7ee81a3f8ab351ea861bdf7d948493</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Adult</topic><topic>Botulinum Toxins, Type A - administration & dosage</topic><topic>Humans</topic><topic>Injections, Intramuscular</topic><topic>Male</topic><topic>Neck Muscles - drug effects</topic><topic>Neuromuscular Agents - therapeutic use</topic><topic>Regional Blood Flow - drug effects</topic><topic>Subclavian Artery - physiopathology</topic><topic>Thoracic Outlet Syndrome - drug therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Danielson, Kirk</creatorcontrib><creatorcontrib>Odderson, Ib R</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Toxicology Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>American journal of physical medicine & rehabilitation</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Danielson, Kirk</au><au>Odderson, Ib R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Botulinum toxin type A improves blood flow in vascular thoracic outlet syndrome</atitle><jtitle>American journal of physical medicine & rehabilitation</jtitle><addtitle>Am J Phys Med Rehabil</addtitle><date>2008-11</date><risdate>2008</risdate><volume>87</volume><issue>11</issue><spage>956</spage><epage>959</epage><pages>956-959</pages><issn>0894-9115</issn><eissn>1537-7385</eissn><abstract>A 28-yr-old man, diagnosed with vascular thoracic outlet syndrome, had his right anterior scalene muscle injected with botulinum toxin type A under ultrasound guidance. 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subjects | Adult Botulinum Toxins, Type A - administration & dosage Humans Injections, Intramuscular Male Neck Muscles - drug effects Neuromuscular Agents - therapeutic use Regional Blood Flow - drug effects Subclavian Artery - physiopathology Thoracic Outlet Syndrome - drug therapy |
title | Botulinum toxin type A improves blood flow in vascular thoracic outlet syndrome |
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