A Novel C-Terminal Mutation in Gsdma3 (C+/H-) Leads to Alopecia and Corneal Inflammatory Response in Mice

Mutations in the gene encoding Gasdermin A3 (Gsdma3) have been described to cause severe skin phenotypes, including loss of sebaceous glands and alopecia, in mice. We discovered a novel C-terminal mutation in Gsdma3 in a new mouse line and characterized a less frequently reported corneal phenotype,...

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Veröffentlicht in:	Investigative ophthalmology & visual science 2018-01, Vol.59 (1), p.561-571
Hauptverfasser:	Swirski, Sebastian, Röger, Carsten, Pienkowska-Schelling, Aldona, Ihlenburg, Cynthia, Fischer, Gösta, May, Oliver, Vorm, Mariann, Owczarek-Lipska, Marta, Neidhardt, John
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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