Potential of delphinidin-3-rutinoside extracted from Solanum melongena L. as promoter of osteoblastic MC3T3-E1 function and antagonist of oxidative damage

Purpose Increasing evidence suggests the potential use of natural antioxidant compounds in the prevention/treatment of osteoporosis. This study was undertaken to investigate the effects of purified delphinidin-3-rutinoside (D3R), isolated from Solanum melongena L., on osteoblast viability and differ...

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Veröffentlicht in:	European journal of nutrition 2019-04, Vol.58 (3), p.1019-1032
Hauptverfasser:	Casati, Lavinia, Pagani, Francesca, Fibiani, Marta, Lo Scalzo, Roberto, Sibilia, Valeria
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Phosphatidylinositol 3-kinase Age AKT protein Alkaline phosphatase Animals Anthocyanins - pharmacology Antioxidants Antioxidants - pharmacology Apoptosis Butyl hydroperoxide Cell Line - drug effects Cell Survival Cells, Cultured Chemistry Chemistry and Materials Science Collagen (type I) Cytoskeleton Glutathione Intracellular Mice Nutrition Original Contribution Osteoblastogenesis Osteoblasts Osteoblasts - drug effects Osteocalcin Osteoporosis Osteoprotegerin Oxidative stress Oxidative Stress - drug effects Phalloidin Plant Extracts - pharmacology Reactive oxygen species Solanum melongena TRANCE protein
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