Asymmetric Synthesis of Chiral Acyclic Purine Nucleosides Containing a Hemiaminal Ester Moiety via Three-Component Dynamic Kinetic Resolution

An efficient route to construct chiral acyclic purine nucleosides containing a hemiaminal ester moiety is reported via three-component dynamic kinetic resolution of purines, aldehydes, and acid anhydrides. The procedure provides diverse chiral acyclic purine nucleoside analogues in a regioselective...

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Veröffentlicht in:	Organic letters 2018-02, Vol.20 (4), p.1212-1215
Hauptverfasser:	Xie, Ming-Sheng, Chen, Yang-Guang, Wu, Xiao-Xia, Qu, Gui-Rong, Guo, Hai-Ming
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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