Discrete and Continuum Approximations for Collective Cell Migration in a Scratch Assay with Cell Size Dynamics

Scratch assays are routinely used to study the collective spreading of cell populations. In general, the rate at which a population of cells spreads is driven by the combined effects of cell migration and proliferation. To examine the effects of cell migration separately from the effects of cell pro...

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Veröffentlicht in:	Bulletin of mathematical biology 2018-04, Vol.80 (4), p.738-757
Hauptverfasser:	Matsiaka, Oleksii M., Penington, Catherine J, Baker, Ruth E., Simpson, Matthew J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Approximation Assaying Cell Adhesion Cell adhesion & migration Cell Biology Cell growth Cell migration Cell Migration Assays - methods Cell Movement Cell proliferation Cell Proliferation - drug effects Cell Size Descriptions Differential equations Evolution Humans Life Sciences Male Mathematical analysis Mathematical and Computational Biology Mathematical Concepts Mathematical models Mathematics Mathematics and Statistics Mitomycin - pharmacology Mitomycin C Model accuracy Models, Biological Original Article PC-3 Cells Stochastic models Stochastic Processes Stochasticity
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