Gut microbiome may contribute to insulin resistance and systemic inflammation in obese rodents: a meta-analysis

A number of studies have associated obesity with altered gut microbiota, although results are discordant regarding compositional changes in the gut microbiota of obese animals. Herein we used a meta-analysis to obtain an unbiased evaluation of structural and functional changes of the gut microbiota...

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Veröffentlicht in:	Physiological genomics 2018-04, Vol.50 (4), p.244-254
Hauptverfasser:	Jiao, Na, Baker, Susan S, Nugent, Colleen A, Tsompana, Maria, Cai, Liting, Wang, Yong, Buck, Michael J, Genco, Robert J, Baker, Robert D, Zhu, Ruixin, Zhu, Lixin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Animals Bacilli Bacteroidetes Biosynthesis Carbohydrate metabolism Diet, High-Fat - adverse effects Dysbacteriosis Fatty acids Firmicutes Gastrointestinal Microbiome - physiology High fat diet Inflammation Inflammation - immunology Inflammation - microbiology Insulin Insulin resistance Insulin Resistance - physiology Intestinal microflora Lipid metabolism Meta-analysis Metabolism Microbiomes Microbiota Obesity Obesity - immunology Obesity - microbiology Pentose phosphate pathway Polysaccharides Pyruvic acid Rodentia Structure-function relationships
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