Asymmetric Catalytic Double Michael Additions for the Synthesis of Spirooxindoles

Asymmetric cascade double Michael additions to construct 2′‐substituted 3,3′‐spirooxindoles by using a chiral guanidine organocatalyst has been developed. A series of spirooxindole derivatives containing dihydrofuran or pyrrolidine subunits were obtained with good to excellent diastereo‐ and enantio...

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Veröffentlicht in:	Chemistry : a European journal 2018-03, Vol.24 (15), p.3703-3706
Hauptverfasser:	Kang, Tengfei, Zhao, Peng, Yang, Jian, Lin, Lili, Feng, Xiaoming, Liu, Xiaohua
Format:	Artikel
Sprache:	eng
Schlagworte:	Aliphatic compounds asymmetric catalysis Asymmetric synthesis Asymmetry Catalysis Chemical synthesis Chemistry conjugated addition Guanidine Pyrrolidine salacin spirooxindole
Online-Zugang:	Volltext
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