WNT10B mutations associated with isolated dental anomalies

Isolated hypodontia is the most common human malformation. It is caused by heterozygous variants in various genes, with heterozygous WNT10A variants being the most common cause. WNT10A and WNT10B are paralogs that likely evolved from a common ancestral gene after its duplication. Recently, an associ...

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Veröffentlicht in:	Clinical genetics 2018-05, Vol.93 (5), p.992-999
Hauptverfasser:	Kantaputra, P.N., Hutsadaloi, A., Kaewgahya, M., Intachai, W., German, R., Koparal, M., Leethanakul, C., Tolun, A., Ketudat Cairns, J.R.
Format:	Artikel
Sprache:	eng
Schlagworte:	AP-2 protein Dental pulp Dental roots hypodontia microdontia Mutation oligodontia split hand‐foot malformation taurodontism Teeth tooth agenesis WNT10A
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