Calcium Release Mediated by Redox-Sensitive RyR2 Channels Has a Central Role in Hippocampal Structural Plasticity and Spatial Memory

Previous studies indicate that hippocampal synaptic plasticity and spatial memory processes entail calcium release from intracellular stores mediated by ryanodine receptor (RyR) channels. In particular, RyR-mediated Ca release is central for the dendritic spine remodeling induced by brain-derived ne...

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Veröffentlicht in:	Antioxidants & redox signaling 2018-10, Vol.29 (12), p.1125-1146
Hauptverfasser:	More, Jamileth Y, Bruna, Barbara A, Lobos, Pedro E, Galaz, José L, Figueroa, Paula L, Namias, Silvia, Sánchez, Gina L, Barrientos, Genaro C, Valdés, José L, Paula-Lima, Andrea C, Hidalgo, Cecilia, Adasme, Tatiana
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal behavior Antioxidants Antisense oligonucleotides Brain Brain-derived neurotrophic factor Calcium Calcium (intracellular) Calcium channels Calcium ions Channels CYBB protein Dendritic spines Gene expression Glutamic acid receptors (ionotropic) Hippocampal plasticity Hippocampus Innovations Memory tasks Mental task performance N-Methyl-D-aspartic acid receptors NAD(P)H oxidase Nitric oxide Nitric-oxide synthase Oxidase Plasticity Protein biosynthesis Protein synthesis Proteins Reactive oxygen species Reagents Receptors Ribonucleic acid RNA Ryanodine receptors Signal processing Spatial analysis Spatial memory Spine Synaptic plasticity
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