Staged surgical treatment of extremity lymphedema with dual gastroepiploic vascularized lymph node transfers followed by suction‐assisted lipectomy—A prospective study
Background Both physiologic and excisional procedures have been described for the treatment of lymphedema. However, there exist few reports that combine these procedures. The objective of this study was to evaluate the effectiveness of combining vascularized lymph node transfer (VLNT) with suction‐a...
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Veröffentlicht in: | Journal of surgical oncology 2018-05, Vol.117 (6), p.1148-1156 |
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creator | Agko, Mouchammed Ciudad, Pedro Chen, Hung‐Chi |
description | Background
Both physiologic and excisional procedures have been described for the treatment of lymphedema. However, there exist few reports that combine these procedures. The objective of this study was to evaluate the effectiveness of combining vascularized lymph node transfer (VLNT) with suction‐assisted lipectomy (SAL) in a staged manner for the treatment of extremity lymphedema.
Methods
Patients with unilateral late stage II lymphedema (International Society of Lymphology), who consented to staged surgical treatment, were evaluated prospectively. Between 2014 and 2015, 12 female patients with upper (n = 6) or lower (n = 6) extremity lymphedema completed the treatment protocol. Primary outcomes evaluated included limb size and number of infectious episodes. In addition, compression garment usage was analyzed.
Results
The overall circumference reduction rate was on average 37.9% after VLNT and increased to 96.4% after SAL. While all patients had experienced at least one infectious episode prior to surgical treatment, only one patient did so after VLNT and none after SAL. All patients were able to eventually discontinue compression therapy.
Conclusion
VLNT followed by SAL can allow patients with late Stage II lymphedema achieve near normal limb size and eradication of infectious episodes. At follow‐up, these desirable outcomes were maintained well after discontinuation of compression therapy. |
doi_str_mv | 10.1002/jso.24969 |
format | Article |
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Both physiologic and excisional procedures have been described for the treatment of lymphedema. However, there exist few reports that combine these procedures. The objective of this study was to evaluate the effectiveness of combining vascularized lymph node transfer (VLNT) with suction‐assisted lipectomy (SAL) in a staged manner for the treatment of extremity lymphedema.
Methods
Patients with unilateral late stage II lymphedema (International Society of Lymphology), who consented to staged surgical treatment, were evaluated prospectively. Between 2014 and 2015, 12 female patients with upper (n = 6) or lower (n = 6) extremity lymphedema completed the treatment protocol. Primary outcomes evaluated included limb size and number of infectious episodes. In addition, compression garment usage was analyzed.
Results
The overall circumference reduction rate was on average 37.9% after VLNT and increased to 96.4% after SAL. While all patients had experienced at least one infectious episode prior to surgical treatment, only one patient did so after VLNT and none after SAL. All patients were able to eventually discontinue compression therapy.
Conclusion
VLNT followed by SAL can allow patients with late Stage II lymphedema achieve near normal limb size and eradication of infectious episodes. At follow‐up, these desirable outcomes were maintained well after discontinuation of compression therapy.</description><identifier>ISSN: 0022-4790</identifier><identifier>EISSN: 1096-9098</identifier><identifier>DOI: 10.1002/jso.24969</identifier><identifier>PMID: 29355987</identifier><language>eng</language><publisher>United States: Wiley Subscription Services, Inc</publisher><subject>Abdomen - surgery ; Adult ; Aged ; Cancer surgery ; Compression therapy ; Extremities - surgery ; Female ; Follow-Up Studies ; Gastroepiploic Artery ; Humans ; Lipectomy - methods ; Lymph Nodes - blood supply ; Lymph Nodes - transplantation ; Lymphatic system ; Lymphedema ; Lymphedema - surgery ; lymphedema treatment ; Middle Aged ; Postoperative Complications - surgery ; Prognosis ; Prospective Studies ; staged combined surgical treatment ; Suction ; suction assisted lipectomy ; vascularized lymph node transfer</subject><ispartof>Journal of surgical oncology, 2018-05, Vol.117 (6), p.1148-1156</ispartof><rights>2018 Wiley Periodicals, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2689-71b2677fba2919959529e1bc1de2033d6445c7077c92cc3508529c2e70c8bf9c3</citedby><cites>FETCH-LOGICAL-c2689-71b2677fba2919959529e1bc1de2033d6445c7077c92cc3508529c2e70c8bf9c3</cites><orcidid>0000-0003-4646-2676</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fjso.24969$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fjso.24969$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27903,27904,45553,45554</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29355987$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Agko, Mouchammed</creatorcontrib><creatorcontrib>Ciudad, Pedro</creatorcontrib><creatorcontrib>Chen, Hung‐Chi</creatorcontrib><title>Staged surgical treatment of extremity lymphedema with dual gastroepiploic vascularized lymph node transfers followed by suction‐assisted lipectomy—A prospective study</title><title>Journal of surgical oncology</title><addtitle>J Surg Oncol</addtitle><description>Background
Both physiologic and excisional procedures have been described for the treatment of lymphedema. However, there exist few reports that combine these procedures. The objective of this study was to evaluate the effectiveness of combining vascularized lymph node transfer (VLNT) with suction‐assisted lipectomy (SAL) in a staged manner for the treatment of extremity lymphedema.
Methods
Patients with unilateral late stage II lymphedema (International Society of Lymphology), who consented to staged surgical treatment, were evaluated prospectively. Between 2014 and 2015, 12 female patients with upper (n = 6) or lower (n = 6) extremity lymphedema completed the treatment protocol. Primary outcomes evaluated included limb size and number of infectious episodes. In addition, compression garment usage was analyzed.
Results
The overall circumference reduction rate was on average 37.9% after VLNT and increased to 96.4% after SAL. While all patients had experienced at least one infectious episode prior to surgical treatment, only one patient did so after VLNT and none after SAL. All patients were able to eventually discontinue compression therapy.
Conclusion
VLNT followed by SAL can allow patients with late Stage II lymphedema achieve near normal limb size and eradication of infectious episodes. At follow‐up, these desirable outcomes were maintained well after discontinuation of compression therapy.</description><subject>Abdomen - surgery</subject><subject>Adult</subject><subject>Aged</subject><subject>Cancer surgery</subject><subject>Compression therapy</subject><subject>Extremities - surgery</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Gastroepiploic Artery</subject><subject>Humans</subject><subject>Lipectomy - methods</subject><subject>Lymph Nodes - blood supply</subject><subject>Lymph Nodes - transplantation</subject><subject>Lymphatic system</subject><subject>Lymphedema</subject><subject>Lymphedema - surgery</subject><subject>lymphedema treatment</subject><subject>Middle Aged</subject><subject>Postoperative Complications - surgery</subject><subject>Prognosis</subject><subject>Prospective Studies</subject><subject>staged combined surgical treatment</subject><subject>Suction</subject><subject>suction assisted lipectomy</subject><subject>vascularized lymph node transfer</subject><issn>0022-4790</issn><issn>1096-9098</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kc9u1DAQhy0EokvhwAsgS1zgkNZ2_jhzrCoooEo9FM6R40y2XjlxsJ1uw6mP0ANvwVv1SfB2CwckTtZovvk8ox8hrzk74oyJ401wR6KACp6QFWdQZcCgfkpWqSeyQgI7IC9C2DDGAKriOTkQkJcl1HJFfl1GtcaOhtmvjVaWRo8qDjhG6nqKN6kcTFyoXYbpCjscFN2aeEW7ObFrFaJ3OJnJOqPptQp6tsqbH0n4MEBH12FSqjH06APtnbVum7rtkn7U0bjx_vZOhWBC3M2YCXV0w3J_-_OETt6FXW2ukYY4d8tL8qxXNuCrx_eQfPv44evpp-z84uzz6cl5pkVVQyZ5Kyop-1YJ4AAllAKQt5p3KFied1VRlFoyKTUIrfOS1QnQAiXTdduDzg_Ju703bfB9xhCbwQSN1qoR3RwaDjUAzyWIhL79B9242Y9pu0awUnKZNqoT9X5P6XRS8Ng3kzeD8kvDWbNLsEkJNg8JJvbNo3FuB-z-kn8iS8DxHtgai8v_Tc2Xy4u98je1wawS</recordid><startdate>20180501</startdate><enddate>20180501</enddate><creator>Agko, Mouchammed</creator><creator>Ciudad, Pedro</creator><creator>Chen, Hung‐Chi</creator><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-4646-2676</orcidid></search><sort><creationdate>20180501</creationdate><title>Staged surgical treatment of extremity lymphedema with dual gastroepiploic vascularized lymph node transfers followed by suction‐assisted lipectomy—A prospective study</title><author>Agko, Mouchammed ; Ciudad, Pedro ; Chen, Hung‐Chi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2689-71b2677fba2919959529e1bc1de2033d6445c7077c92cc3508529c2e70c8bf9c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Abdomen - surgery</topic><topic>Adult</topic><topic>Aged</topic><topic>Cancer surgery</topic><topic>Compression therapy</topic><topic>Extremities - surgery</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Gastroepiploic Artery</topic><topic>Humans</topic><topic>Lipectomy - methods</topic><topic>Lymph Nodes - blood supply</topic><topic>Lymph Nodes - transplantation</topic><topic>Lymphatic system</topic><topic>Lymphedema</topic><topic>Lymphedema - surgery</topic><topic>lymphedema treatment</topic><topic>Middle Aged</topic><topic>Postoperative Complications - surgery</topic><topic>Prognosis</topic><topic>Prospective Studies</topic><topic>staged combined surgical treatment</topic><topic>Suction</topic><topic>suction assisted lipectomy</topic><topic>vascularized lymph node transfer</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Agko, Mouchammed</creatorcontrib><creatorcontrib>Ciudad, Pedro</creatorcontrib><creatorcontrib>Chen, Hung‐Chi</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of surgical oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Agko, Mouchammed</au><au>Ciudad, Pedro</au><au>Chen, Hung‐Chi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Staged surgical treatment of extremity lymphedema with dual gastroepiploic vascularized lymph node transfers followed by suction‐assisted lipectomy—A prospective study</atitle><jtitle>Journal of surgical oncology</jtitle><addtitle>J Surg Oncol</addtitle><date>2018-05-01</date><risdate>2018</risdate><volume>117</volume><issue>6</issue><spage>1148</spage><epage>1156</epage><pages>1148-1156</pages><issn>0022-4790</issn><eissn>1096-9098</eissn><abstract>Background
Both physiologic and excisional procedures have been described for the treatment of lymphedema. However, there exist few reports that combine these procedures. The objective of this study was to evaluate the effectiveness of combining vascularized lymph node transfer (VLNT) with suction‐assisted lipectomy (SAL) in a staged manner for the treatment of extremity lymphedema.
Methods
Patients with unilateral late stage II lymphedema (International Society of Lymphology), who consented to staged surgical treatment, were evaluated prospectively. Between 2014 and 2015, 12 female patients with upper (n = 6) or lower (n = 6) extremity lymphedema completed the treatment protocol. Primary outcomes evaluated included limb size and number of infectious episodes. In addition, compression garment usage was analyzed.
Results
The overall circumference reduction rate was on average 37.9% after VLNT and increased to 96.4% after SAL. While all patients had experienced at least one infectious episode prior to surgical treatment, only one patient did so after VLNT and none after SAL. All patients were able to eventually discontinue compression therapy.
Conclusion
VLNT followed by SAL can allow patients with late Stage II lymphedema achieve near normal limb size and eradication of infectious episodes. At follow‐up, these desirable outcomes were maintained well after discontinuation of compression therapy.</abstract><cop>United States</cop><pub>Wiley Subscription Services, Inc</pub><pmid>29355987</pmid><doi>10.1002/jso.24969</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0003-4646-2676</orcidid></addata></record> |
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subjects | Abdomen - surgery Adult Aged Cancer surgery Compression therapy Extremities - surgery Female Follow-Up Studies Gastroepiploic Artery Humans Lipectomy - methods Lymph Nodes - blood supply Lymph Nodes - transplantation Lymphatic system Lymphedema Lymphedema - surgery lymphedema treatment Middle Aged Postoperative Complications - surgery Prognosis Prospective Studies staged combined surgical treatment Suction suction assisted lipectomy vascularized lymph node transfer |
title | Staged surgical treatment of extremity lymphedema with dual gastroepiploic vascularized lymph node transfers followed by suction‐assisted lipectomy—A prospective study |
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