Chd7 Is Critical for Early T-Cell Development and Thymus Organogenesis in Zebrafish

Coloboma, heart defect, atresia choanae, retarded growth and development, genital hypoplasia, ear anomalies/deafness (CHARGE) syndrome is a congenital disorder affecting multiple organs and mainly caused by mutations in CHD7, a gene encoding a chromatin-remodeling protein. Immunodeficiency and reduc...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The American journal of pathology 2018-04, Vol.188 (4), p.1043-1058
Hauptverfasser:	Liu, Zhi-Zhi, Wang, Zi-Long, Choi, Tae-Ik, Huang, Wen-Ting, Wang, Han-Tsing, Han, Ying-Ying, Zhu, Lou-Yin, Kim, Hyun-Taek, Choi, Jung-Hwa, Lee, Jin-Soo, Kim, Hyung-Goo, Zhao, Jian, Chen, Yue, Lu, Zhuo, Tian, Xiao-Li, Pan, Bing-Xing, Li, Bao-Ming, Kim, Cheol-Hee, Xu, Hong A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Genetically Modified Apoptosis - drug effects Base Sequence Bone Morphogenetic Proteins - metabolism Branchial Region - drug effects Branchial Region - embryology Cell Movement - drug effects Cell Proliferation - drug effects Chemokines - metabolism DNA Helicases - deficiency DNA Helicases - metabolism DNA-Binding Proteins - deficiency DNA-Binding Proteins - metabolism Embryo, Nonmammalian - metabolism Epithelial Cells - metabolism Forkhead Transcription Factors - metabolism Hematopoietic Stem Cells - metabolism Morpholinos - pharmacology Mutation - genetics Neural Crest - pathology Organogenesis Phenotype Signal Transduction T-Lymphocytes - cytology Thymus Gland - cytology Thymus Gland - growth & development Zebrafish - embryology Zebrafish - metabolism Zebrafish Proteins - deficiency Zebrafish Proteins - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!