In silico identification and experimental validation of amino acid motifs required for the Rho-of-plants GTPase-mediated activation of receptor-like cytoplasmic kinases

Key message Several amino acid motifs required for Rop-dependent activity were found to form a common surface on RLCKVI_A kinases. This indicates a unique mechanism for Rho-type GTPase-mediated kinase activation in plants. Rho-of-plants (Rop) G-proteins are implicated in the regulation of various ce...

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Veröffentlicht in:	Plant cell reports 2018-04, Vol.37 (4), p.627-639
Hauptverfasser:	Lajkó, Dézi Bianka, Valkai, Ildikó, Domoki, Mónika, Ménesi, Dalma, Ferenc, Györgyi, Ayaydin, Ferhan, Fehér, Attila
Format:	Artikel
Sprache:	eng
Schlagworte:	Activation Algae Algal Proteins - genetics Algal Proteins - metabolism Amino Acid Motifs - genetics Amino Acid Sequence Amino acids Aquatic plants Binding Biomedical and Life Sciences Biotechnology Cdc42 protein Cell Biology Chlamydomonas reinhardtii - genetics Chlamydomonas reinhardtii - metabolism Computer Simulation Data mining Data processing GTP-Binding Proteins - genetics GTP-Binding Proteins - metabolism Guanosine triphosphatases Kinases Life Sciences Models, Molecular Original Article Phosphorylation Plant Biochemistry Plant Proteins - genetics Plant Proteins - metabolism Plant Sciences Polarity Protein Binding Protein Domains Protein Kinases - chemistry Protein Kinases - genetics Protein Kinases - metabolism Proteins Sequence Homology, Amino Acid Signal transduction Signaling Two-Hybrid System Techniques Yeast Yeasts
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