Mean High-Dose l-Thyroxine Treatment Is Efficient and Safe to Achieve a Normal IQ in Young Adult Patients With Congenital Hypothyroidism

Abstract Context The optimal levothyroxine (LT4) dose to treat congenital hypothyroidism (CH) remains unclear, with debate over whether higher starting doses (>10 µg/kg) are necessary and safe for a normal intelligence quotient (IQ). Objective To examine psychomotor, metabolic, and quality of lif...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The journal of clinical endocrinology and metabolism 2018-04, Vol.103 (4), p.1459-1469
Hauptverfasser:	Aleksander, Paulina E, Brückner-Spieler, Michaela, Stoehr, Anne-Marie, Lankes, Erwin, Kühnen, Peter, Schnabel, Dirk, Ernert, Andrea, Stäblein, Walter, Craig, Maria E, Blankenstein, Oliver, Grüters, Annette, Krude, Heiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adolescents Age Anthropometry Body mass Body Mass Index Carotid Intima-Media Thickness Central nervous system Cognitive ability Congenital diseases Congenital Hypothyroidism - blood Congenital Hypothyroidism - drug therapy Congenital Hypothyroidism - psychology Cross-Sectional Studies Female Humans Hypothyroidism Infant, Newborn Intelligence Intelligence - drug effects Intelligence tests Male Medical screening Metabolism Neonatal Screening Patients Quality of Life Siblings Thyroid-stimulating hormone Thyroxine Thyroxine - administration & dosage Thyroxine - blood Thyroxine - therapeutic use Triiodothyronine - blood Wechsler Scales Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!