Myocardial Inflammation Predicts Remodeling and Neuroinflammation After Myocardial Infarction

The local inflammatory tissue response after acute myocardial infarction (MI) determines subsequent healing. Systemic interaction may induce neuroinflammation as a precursor to neurodegeneration. This study sought to assess the influence of MI on cardiac and brain inflammation using noninvasive posi...

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Veröffentlicht in:	Journal of the American College of Cardiology 2018-01, Vol.71 (3), p.263-275
Hauptverfasser:	Thackeray, James T., Hupe, Henri C., Wang, Yong, Bankstahl, Jens P., Berding, Georg, Ross, Tobias L., Bauersachs, Johann, Wollert, Kai C., Bengel, Frank M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin-converting enzyme inhibitors Animal cognition Animals Brain Brain - diagnostic imaging Brain - immunology Cardiology Cardiomyocytes Cardiovascular disease Cognitive ability Coronary artery Coronary artery disease Coronary vessels Cytokines Dementia Dosage Enzyme inhibitors Forecasting Heart Heart attacks Heart diseases Heart failure Hypertension Immune response Infiltration Inflammation Inflammation - diagnostic imaging Inflammation - physiopathology Macrophages Medical imaging Mice Mice, Inbred C57BL Microglia Mitochondria Molecular Imaging - methods Myocardial infarction Myocardial Infarction - diagnostic imaging Myocardial Infarction - immunology Myocardium - immunology Myocardium - pathology Neurodegeneration Neuroimaging Neurology Ostomy Patients Peptidyl-dipeptidase A Positron emission Positron emission tomography Proteins Surgery Territory Tomography Ventricle Ventricular Remodeling - physiology
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