The dynamics of a serum steroid profile after stimulation with intravenous ACTH

•An extended steroid profile displays highly dynamic response to IV ACTH stimulation.•Far more pronounced relative increase of corticosterone compared to cortisol.•Corticosterone to be investigated as a novel marker of biochemical stress response. Stimulation with intravenous adrenocorticotropic hor...

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Veröffentlicht in:	Journal of pharmaceutical and biomedical analysis 2018-03, Vol.151, p.159-163
Hauptverfasser:	Lindner, Johanna M., Suhr, Anna Catharina, Grimm, Stefanie H., Möhnle, Patrick, Vogeser, Michael, Briegel, Josef
Format:	Artikel
Sprache:	eng
Schlagworte:	ACTH stimulation test Administration, Intravenous Adrenal Cortex Hormones - blood Adrenocorticotropic Hormone - administration & dosage Adult Biochemical stress response Chromatography, Liquid - methods Corticosteroid profiling Corticosterone Corticosterone - blood Cortisone - blood Female Humans Hydrocortisone - blood LC–MS/MS Male Middle Aged Tandem Mass Spectrometry - methods
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