Structural basis of RNA polymerase III transcription initiation

RNA polymerase (Pol) III transcribes essential non-coding RNAs, including the entire pool of transfer RNAs, the 5S ribosomal RNA and the U6 spliceosomal RNA, and is often deregulated in cancer cells. The initiation of gene transcription by Pol III requires the activity of the transcription factor TF...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nature (London) 2018-01, Vol.553 (7688), p.301-306
Hauptverfasser:	Abascal-Palacios, Guillermo, Ramsay, Ewan Phillip, Beuron, Fabienne, Morris, Edward, Vannini, Alessandro
Format:	Artikel
Sprache:	eng
Schlagworte:	101/28 631/337/1644 631/337/572 631/45/147 631/45/500 631/535/1258/1259 82 82/83 Analysis Cancer Chemical properties Cryoelectron Microscopy Deoxyribonucleic acid DNA DNA - chemistry DNA - metabolism DNA - ultrastructure DNA binding proteins DNA-directed RNA polymerase Electron microscopy Genes Genetic research Humanities and Social Sciences Models, Molecular Molecular modelling Molecular structure multidisciplinary Nucleic Acid Conformation Promoter Regions, Genetic Protein structure Protein Subunits - chemistry Protein Subunits - metabolism Ribonucleic acid RNA RNA polymerase RNA Polymerase I - chemistry RNA polymerase II RNA Polymerase II - chemistry RNA Polymerase III - chemistry RNA Polymerase III - metabolism RNA Polymerase III - ultrastructure RNA polymerases rRNA 5S Saccharomyces cerevisiae - chemistry Saccharomyces cerevisiae - ultrastructure Saccharomyces cerevisiae Proteins - chemistry Saccharomyces cerevisiae Proteins - metabolism Saccharomyces cerevisiae Proteins - ultrastructure Science Structure Templates, Genetic Transcription (Genetics) Transcription Factor TFIIIB - chemistry Transcription Factor TFIIIB - metabolism Transcription Factor TFIIIB - ultrastructure Transcription Factors, TFII - chemistry Transcription Initiation, Genetic
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!