Copper(II)-Mediated ortho-Selective C(sp2)–H Tandem Alkynylation/Annulation and ortho-Hydroxylation of Anilides with 2‑Aminophenyl‑1H‑pyrazole as a Directing Group

2-Aminophenyl-1H-pyrazole has been identified as a viable directing group to promote copper­(II)-mediated ortho-selective sp2 C–H bond tandem alkynylation/annulation of anilides with terminal alkynes to offer arylmethylene isoindolinones. Meanwhile, copper­(II)-mediated ortho-selective sp2 C–H hydro...

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Veröffentlicht in:Journal of organic chemistry 2018-02, Vol.83 (4), p.2382-2388
Hauptverfasser: Lee, Wan-Chen Cindy, Wang, Wei, Li, Jie Jack
Format: Artikel
Sprache:eng
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