Development of a Cytopathic Effect-Based Phenotypic Screening Assay against Cryptosporidium

Cryptosporidiosis is a diarrheal disease predominantly caused by Cryptosporidium parvum (Cp) and Cryptosporidium hominis (Ch), apicomplexan parasites which infect the intestinal epithelial cells of their human hosts. The only approved drug for cryptosporidiosis is nitazoxanide, which shows limited e...

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Veröffentlicht in:	ACS infectious diseases 2018-04, Vol.4 (4), p.635-645
Hauptverfasser:	Chao, Alexander T, Lee, Boon Heng, Wan, Kah Fei, Selva, Jeremy, Zou, Bin, Gedeck, Peter, Beer, David John, Diagana, Thierry T, Bonamy, Ghislain M. C, Manjunatha, Ujjini H
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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