Long non-coding RNA XIST promotes TGF-β-induced epithelial-mesenchymal transition by regulating miR-367/141-ZEB2 axis in non-small-cell lung cancer

Growing evidence shows that lncRNA XIST functions as an oncogene accelerating tumor progression. Transforming growth factor β (TGF-β)-induced epithelial-mesenchymal transition (EMT) plays a key role in tumor metastasis. However, it is still unclear whether lncRNA XIST is implicated in TGF-β-induced...

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Veröffentlicht in:	Cancer letters 2018-04, Vol.418, p.185-195
Hauptverfasser:	Li, Chang, Wan, Liang, Liu, Zeyi, Xu, Guangquan, Wang, Shengjie, Su, Zhiyue, Zhang, Yingxi, Zhang, Cuijuan, Liu, Xia, Lei, Zhe, Zhang, Hong-Tao
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal tissues Cell adhesion & migration Cell migration EMT Gene expression lncRNA XIST Lung cancer Mesenchyme Metastases Metastasis MicroRNAs miR-141 mRNA Non-coding RNA Non-small cell lung carcinoma Non-small-cell lung cancer (NSCLC) Transforming growth factor Transforming growth factor beta (TGF-β) Transforming growth factor-b Tumors
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