Treatment with sublingual desmopressin in two infants with hydranencephaly and central diabetes insipidus

Treatment with sublingual desmopressin in two infants with hydranencephaly and central diabetes insipidus

Central diabetes insipidus is a rare disease in children caused by a deficiency of vasopressin. Its main clinical manifestations are polyuria and polydipsia. Brain malformations are one of the main causes. Desmopressin is the synthetic drug of choice for the treatment. One of the routes of administr...

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Veröffentlicht in:Archivos argentinos de pediatría 2018-02, Vol.116 (1), p.e93-e97
Hauptverfasser: Marín, Gustavo R, Baspineiro, Berta, Vilca, Iris
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creator Marín, Gustavo R
Baspineiro, Berta
Vilca, Iris
description Central diabetes insipidus is a rare disease in children caused by a deficiency of vasopressin. Its main clinical manifestations are polyuria and polydipsia. Brain malformations are one of the main causes. Desmopressin is the synthetic drug of choice for the treatment. One of the routes of administration is sublingual and its use in infants is very limited. We describe two infants with central diabetes insipidus and hydranencephaly who were successfully treated with sublingual desmopressin.
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title Treatment with sublingual desmopressin in two infants with hydranencephaly and central diabetes insipidus
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