Genetic variation of GRIA3 gene is associated with vulnerability to methamphetamine dependence and its associated psychosis

Methamphetamine (METH) is an addictive psychostimulant drug commonly leading to schizophrenia-like psychotic symptoms. Disturbances in glutamatergic neurotransmission have been proposed as neurobiological mechanisms and the α-amino-3 hydroxy-5 methyl-4 isoxazole propionic acid (AMPA) glutamate recep...

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Veröffentlicht in:	Journal of psychopharmacology (Oxford) 2018-03, Vol.32 (3), p.309-315
Hauptverfasser:	Iamjan, Sri-arun, Thanoi, Samur, Watiktinkorn, Paritat, Reynolds, Gavin P, Nudmamud-Thanoi, Sutisa
Format:	Artikel
Sprache:	eng
Schlagworte:	Brain-derived neurotrophic factor Drug dependence Gene polymorphism Genetic diversity Genetic variability Genetic variance Genotyping Glutamatergic transmission Glutamic acid receptors Mental disorders Methamphetamine Neurotransmission Propionic acid Psychopharmacology Psychosis Risk factors Schizophrenia α-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid α-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors
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