Chebulinic acid attenuates glutamate-induced HT22 cell death by inhibiting oxidative stress, calcium influx and MAPKs phosphorylation

[Display omitted] Glutamate-induced excitotoxicity and oxidative stress is a major causative factor in neuronal cell death in acute brain injuries and chronic neurodegenerative diseases. The prevention of oxidative stress is a potential therapeutic strategy. Therefore, in the present study, we aimed...

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Veröffentlicht in:	Bioorganic & medicinal chemistry letters 2018-02, Vol.28 (3), p.249-253
Hauptverfasser:	Song, Ji Hoon, Shin, Myoung-Sook, Hwang, Gwi Seo, Oh, Seong Taek, Hwang, Jung Jin, Kang, Ki Sung
Format:	Artikel
Sprache:	eng
Schlagworte:	Calcium Chebulinic acid Glutamate HT22 cells Mitogen-activated protein kinase Reactive oxygen species
Online-Zugang:	Volltext
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