Pregabalin as adjunctive therapy in benzodiazepine discontinuation

PURPOSE.The available evidence for the use of pregabalin as adjunctive therapy in the discontinuation of benzodiazepines is reviewed. SUMMARY.Pregabalin has been studied as an adjunctive pharmacologic treatment for the discontinuation of long-term benzodiazepine use. Unlike carbamazepine, pregabalin...

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Veröffentlicht in:	American journal of health-system pharmacy 2018-01, Vol.75 (2), p.67-71
Hauptverfasser:	Caniff, Kaylee, Telega, Emily, Bostwick, Jolene R, Gardner, Kristen N
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Anxiety Agents - administration & dosage Anti-Anxiety Agents - adverse effects Anxiety Benzodiazepines Benzodiazepines - administration & dosage Benzodiazepines - adverse effects Calcium Calcium channels Calcium channels (voltage-gated) Carbamazepine Cognitive ability Dosage and administration Drug abuse Drug therapy Drug Therapy, Combination Humans Neurotransmitters Observational Studies as Topic - methods Pregabalin Pregabalin - administration & dosage Randomized Controlled Trials as Topic - methods Regulatory subunits Substance withdrawal syndrome Substance Withdrawal Syndrome - diagnosis Substance Withdrawal Syndrome - epidemiology Substance Withdrawal Syndrome - prevention & control Withdrawal Withholding Treatment - standards Withholding Treatment - trends
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