Local proliferation maintains a stable pool of tissue-resident memory T cells after antiviral recall responses

Although tissue-resident memory T cells (T RM cells) are critical in fighting infection, their fate after local pathogen re-encounter is unknown. Here we found that skin T RM cells engaged virus-infected cells, proliferated in situ in response to local antigen encounter and did not migrate out of th...

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Veröffentlicht in:Nature immunology 2018-02, Vol.19 (2), p.183-191
Hauptverfasser: Park, Simone L., Zaid, Ali, Hor, Jyh Liang, Christo, Susan N., Prier, Julia E., Davies, Brooke, Alexandre, Yannick O., Gregory, Julia L., Russell, Tiffany A., Gebhardt, Thomas, Carbone, Francis R., Tscharke, David C., Heath, William R., Mueller, Scott N., Mackay, Laura K.
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Sprache:eng
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