Synthesis of Multisubstituted Azatriphenylenes by Iridium-Catalyzed [2 + 2 + 2] Cycloaddition of Biaryl-Linked Diynes with Nitriles

Synthesis of Multisubstituted Azatriphenylenes by Iridium-Catalyzed [2 + 2 + 2] Cycloaddition of Biaryl-Linked Diynes with Nitriles

A convenient synthesis of multisubstituted azatriphenylenes is reported. [Ir­(cod)­Cl]2/diphosphine is an efficient catalyst for the [2 + 2 + 2] cycloaddition of biaryl-linked diynes with nitriles to give multisubstituted azatriphenylenes in high yields. Aromatic, heteroaromatic, aliphatic, and func...

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Veröffentlicht in:Journal of organic chemistry 2018-02, Vol.83 (4), p.1852-1860
Hauptverfasser: Takeuchi, Ryo, Fujisawa, Shunsuke, Yoshida, Yuzo, Sagano, Jun, Hashimoto, Toru, Matsunami, Asuka
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container_end_page 1860
container_issue 4
container_start_page 1852
container_title Journal of organic chemistry
container_volume 83
creator Takeuchi, Ryo
Fujisawa, Shunsuke
Yoshida, Yuzo
Sagano, Jun
Hashimoto, Toru
Matsunami, Asuka
description A convenient synthesis of multisubstituted azatriphenylenes is reported. [Ir­(cod)­Cl]2/diphosphine is an efficient catalyst for the [2 + 2 + 2] cycloaddition of biaryl-linked diynes with nitriles to give multisubstituted azatriphenylenes in high yields. Aromatic, heteroaromatic, aliphatic, and functionalized nitriles could be used for the reaction.
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title Synthesis of Multisubstituted Azatriphenylenes by Iridium-Catalyzed [2 + 2 + 2] Cycloaddition of Biaryl-Linked Diynes with Nitriles
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