Diagnostic Utility of Molecular and Imaging Biomarkers in Cytological Indeterminate Thyroid Nodules

Abstract Indeterminate thyroid cytology (Bethesda III and IV) corresponds to follicular-patterned benign and malignant lesions, which are particularly difficult to differentiate on cytology alone. As ~25% of these nodules harbor malignancy, diagnostic hemithyroidectomy is still custom. However, adva...

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Veröffentlicht in:	Endocrine reviews 2018-04, Vol.39 (2), p.154-191
Hauptverfasser:	de Koster, Elizabeth J, de Geus-Oei, Lioe-Fee, Dekkers, Olaf M, van Engen-van Grunsven, Ilse, Hamming, Jaap, Corssmit, Eleonora P M, Morreau, Hans, Schepers, Abbey, Smit, Jan, Oyen, Wim J G, Vriens, Dennis
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers Cellular biology Computed tomography Cost analysis Cytology Diagnosis Diagnostic Imaging - standards Diagnostic systems Emission analysis Feasibility studies Gene expression Gene mutations Genetic aspects Genetics Geographical variations Glucose Humans Immunocytochemistry Lesions Magnetic resonance imaging Malignancy Medical imaging miRNA Molecular Diagnostic Techniques - standards Mutation Neoplasms Nodules PET imaging Point mutation Positron emission Positron emission tomography Ribonucleic acid RNA Scintigraphy Sensitivity analysis Thyroid Thyroid diseases Thyroid gland Thyroid Nodule - diagnosis Thyroid Nodule - diagnostic imaging Thyroid Nodule - genetics Ultrasonography
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