Think About the Environment: Cellular Reprogramming by the Extracellular Matrix

Think About the Environment: Cellular Reprogramming by the Extracellular Matrix

In this issue of Cell Stem Cell, Yui et al. (2018) show how tissue regeneration is driven by changes in the microenvironment. During intestinal regeneration, the epithelium is reprogrammed into a fetal state by an altered extracellular matrix (ECM), which is dependent on YAP/TAZ activation. In this...

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Veröffentlicht in:Cell stem cell 2018-01, Vol.22 (1), p.7-9
Hauptverfasser: Huels, David J., Medema, Jan Paul
Format: Artikel
Sprache:eng
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Zusammenfassung:In this issue of Cell Stem Cell, Yui et al. (2018) show how tissue regeneration is driven by changes in the microenvironment. During intestinal regeneration, the epithelium is reprogrammed into a fetal state by an altered extracellular matrix (ECM), which is dependent on YAP/TAZ activation. In this issue of Cell Stem Cell, Yui et al. (2018) show how tissue regeneration is driven by changes in the microenvironment. During intestinal regeneration, the epithelium is reprogrammed into a fetal state by an altered extracellular matrix (ECM), which is dependent on YAP/TAZ activation.
ISSN:1934-5909
1875-9777
DOI:10.1016/j.stem.2017.12.006