Differential Expression of Inflammatory and Fibrogenic Genes and Their Regulation by NF-κB Inhibition in a Mouse Model of Chronic Colitis

Fibrosis is a major complication of chronic inflammation, as seen in Crohn’s disease and ulcerative colitis, two forms of inflammatory bowel diseases. To elucidate inflammatory signals that regulate fibrosis, we investigated gene expression changes underlying chronic inflammation and fibrosis in tri...

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Veröffentlicht in:The Journal of immunology (1950) 2007-11, Vol.179 (10), p.6988-7000
Hauptverfasser: Wu, Feng, Chakravarti, Shukti
Format: Artikel
Sprache:eng
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