Towards abolition of immunogenic structures in insect cells: characterization of a honey-bee (Apis mellifera) multi-gene family reveals both an allergy-related core alpha 1,3-fucosyltransferase and the first insect Lewis-histo-blood-group-related antigen-synthesizing enzyme

Glycoproteins from honey-bee (Apis mellifera), such as phospholipase A sub(2) and hyaluronidase, are well-known major bee-venom allergens. They carry N-linked oligosaccharide structures with two types of alpha 1,3-fucosylation: the modification by alpha 1,3-fucose of the innermost core GlcNAc, which...

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Veröffentlicht in:	Biochemical journal 2007-02, Vol.402 (1), p.105-115
Hauptverfasser:	Rendic, D, Klaudiny, J, Stemmer, U, Schmidt, J, Paschinger, K, Wilson, IBH
Format:	Artikel
Sprache:	eng
Schlagworte:	Apis mellifera Drosophila melanogaster
Online-Zugang:	Volltext
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