Action at a distance: epigenetic silencing of large chromosomal regions in carcinogenesis

Despite the completion of the Human Genome Project, we are still far from understanding the molecular events underlying epigenetic change in cancer. Cancer is a disease of the DNA with both genetic and epigenetic changes contributing to changes in gene expression. Epigenetics involves the interplay...

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Veröffentlicht in:	Human molecular genetics 2007-04, Vol.16 (R1), p.R88-R95
1. Verfasser:	Clark, Susan J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Chromatin - genetics Chromosomes, Human - genetics CpG Islands DNA Methylation Epigenesis, Genetic Gene Silencing Humans Neoplasms - genetics RNA, Neoplasm - genetics RNA, Untranslated - genetics
Online-Zugang:	Volltext
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