Genotoxicity biomarkers and acetylcholinesterase activity in natural populations of Mytilus galloprovincialis along a pollution gradient in the Gulf of Oristano (Sardinia, western Mediterranean)
A year-round biomonitoring study on blue mussels ( Mytilus galloprovincialis) was carried out in 4 selected sites along the Gulf of Oristano (Sardinia, Italy): a commercial port ( Port), the outlet of the S'Ena Arrubia and Marceddì lagoons (in the catchment area of intensive agricultural and di...
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| Veröffentlicht in: | Environmental pollution (1987) 2006-07, Vol.142 (1), p.65-72 |
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| container_title | Environmental pollution (1987) |
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| creator | Magni, P. De Falco, G. Falugi, C. Franzoni, M. Monteverde, M. Perrone, E. Sgro, M. Bolognesi, C. |
| description | A year-round biomonitoring study on blue mussels (
Mytilus galloprovincialis) was carried out in 4 selected sites along the Gulf of Oristano (Sardinia, Italy): a commercial port (
Port), the outlet of the
S'Ena Arrubia and
Marceddì lagoons (in the catchment area of intensive agricultural and diary activities, and abandoned mining), and a reference site (
North). Heavy metal concentrations in sediments from
Marceddì were 2–3 to 10–20 times higher in Pb, Cd and Zn, respectively, than those found at
North and
S'Ena Arrubia. Higher values (
P
<
0.05) of micronuclei frequency were detected in mussels from
Marceddì and
Port compared to those detected in mussels from
North and
S'Ena Arrubia. DNA damage in animals from
North was significantly lower than that at the other sites. Results of acetylcholinesterase inhibition consistently showed the strongest effects in mussels from
Port and
Marceddì. Our results suggest that these biomarkers can be used in coastal marine biomonitoring as early signals of exposure and adverse effects along a pollution gradient.
Biomarkers can be useful in coastal marine biomonitoring. |
| doi_str_mv | 10.1016/j.envpol.2005.09.018 |
| format | Article |
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Mytilus galloprovincialis) was carried out in 4 selected sites along the Gulf of Oristano (Sardinia, Italy): a commercial port (
Port), the outlet of the
S'Ena Arrubia and
Marceddì lagoons (in the catchment area of intensive agricultural and diary activities, and abandoned mining), and a reference site (
North). Heavy metal concentrations in sediments from
Marceddì were 2–3 to 10–20 times higher in Pb, Cd and Zn, respectively, than those found at
North and
S'Ena Arrubia. Higher values (
P
<
0.05) of micronuclei frequency were detected in mussels from
Marceddì and
Port compared to those detected in mussels from
North and
S'Ena Arrubia. DNA damage in animals from
North was significantly lower than that at the other sites. Results of acetylcholinesterase inhibition consistently showed the strongest effects in mussels from
Port and
Marceddì. Our results suggest that these biomarkers can be used in coastal marine biomonitoring as early signals of exposure and adverse effects along a pollution gradient.
Biomarkers can be useful in coastal marine biomonitoring.</description><identifier>ISSN: 0269-7491</identifier><identifier>EISSN: 1873-6424</identifier><identifier>DOI: 10.1016/j.envpol.2005.09.018</identifier><identifier>PMID: 16289776</identifier><identifier>CODEN: ENVPAF</identifier><language>eng</language><publisher>Oxford: Elsevier Ltd</publisher><subject>Acetylcholinesterase ; Acetylcholinesterase - analysis ; Acetylcholinesterase - metabolism ; Agriculture ; Alkaline elution ; Animal, plant and microbial ecology ; Animals ; Applied ecology ; bioaccumulation ; Biological and medical sciences ; biomarkers ; Biomonitoring ; cadmium ; DNA Damage ; Ecotoxicology, biological effects of pollution ; Environmental Monitoring - methods ; enzyme activity ; Fundamental and applied biological sciences. Psychology ; General aspects ; genotoxicity ; geochemistry ; Geologic Sediments - chemistry ; Heavy metals ; indicator species ; Italy ; lead ; Marine ; Mediterranean Sea ; Micronucleus test ; Micronucleus Tests ; Mining ; mussels ; Mytilus - chemistry ; Mytilus - enzymology ; Mytilus edulis ; Mytilus galloprovincialis ; sediment contamination ; Water Pollutants, Chemical - toxicity ; water pollution ; Water Pollution - analysis ; zinc</subject><ispartof>Environmental pollution (1987), 2006-07, Vol.142 (1), p.65-72</ispartof><rights>2005 Elsevier Ltd</rights><rights>2006 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c445t-3903c90e35e43e801c67a9116b848e2a68168acc3d7679a9bc2efa4864fd20c33</citedby><cites>FETCH-LOGICAL-c445t-3903c90e35e43e801c67a9116b848e2a68168acc3d7679a9bc2efa4864fd20c33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.envpol.2005.09.018$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17741831$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16289776$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Magni, P.</creatorcontrib><creatorcontrib>De Falco, G.</creatorcontrib><creatorcontrib>Falugi, C.</creatorcontrib><creatorcontrib>Franzoni, M.</creatorcontrib><creatorcontrib>Monteverde, M.</creatorcontrib><creatorcontrib>Perrone, E.</creatorcontrib><creatorcontrib>Sgro, M.</creatorcontrib><creatorcontrib>Bolognesi, C.</creatorcontrib><title>Genotoxicity biomarkers and acetylcholinesterase activity in natural populations of Mytilus galloprovincialis along a pollution gradient in the Gulf of Oristano (Sardinia, western Mediterranean)</title><title>Environmental pollution (1987)</title><addtitle>Environ Pollut</addtitle><description>A year-round biomonitoring study on blue mussels (
Mytilus galloprovincialis) was carried out in 4 selected sites along the Gulf of Oristano (Sardinia, Italy): a commercial port (
Port), the outlet of the
S'Ena Arrubia and
Marceddì lagoons (in the catchment area of intensive agricultural and diary activities, and abandoned mining), and a reference site (
North). Heavy metal concentrations in sediments from
Marceddì were 2–3 to 10–20 times higher in Pb, Cd and Zn, respectively, than those found at
North and
S'Ena Arrubia. Higher values (
P
<
0.05) of micronuclei frequency were detected in mussels from
Marceddì and
Port compared to those detected in mussels from
North and
S'Ena Arrubia. DNA damage in animals from
North was significantly lower than that at the other sites. Results of acetylcholinesterase inhibition consistently showed the strongest effects in mussels from
Port and
Marceddì. Our results suggest that these biomarkers can be used in coastal marine biomonitoring as early signals of exposure and adverse effects along a pollution gradient.
Biomarkers can be useful in coastal marine biomonitoring.</description><subject>Acetylcholinesterase</subject><subject>Acetylcholinesterase - analysis</subject><subject>Acetylcholinesterase - metabolism</subject><subject>Agriculture</subject><subject>Alkaline elution</subject><subject>Animal, plant and microbial ecology</subject><subject>Animals</subject><subject>Applied ecology</subject><subject>bioaccumulation</subject><subject>Biological and medical sciences</subject><subject>biomarkers</subject><subject>Biomonitoring</subject><subject>cadmium</subject><subject>DNA Damage</subject><subject>Ecotoxicology, biological effects of pollution</subject><subject>Environmental Monitoring - methods</subject><subject>enzyme activity</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>General aspects</subject><subject>genotoxicity</subject><subject>geochemistry</subject><subject>Geologic Sediments - chemistry</subject><subject>Heavy metals</subject><subject>indicator species</subject><subject>Italy</subject><subject>lead</subject><subject>Marine</subject><subject>Mediterranean Sea</subject><subject>Micronucleus test</subject><subject>Micronucleus Tests</subject><subject>Mining</subject><subject>mussels</subject><subject>Mytilus - chemistry</subject><subject>Mytilus - enzymology</subject><subject>Mytilus edulis</subject><subject>Mytilus galloprovincialis</subject><subject>sediment contamination</subject><subject>Water Pollutants, Chemical - toxicity</subject><subject>water pollution</subject><subject>Water Pollution - analysis</subject><subject>zinc</subject><issn>0269-7491</issn><issn>1873-6424</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kUFvEzEQhVcIREPhHyDwBQQSCfba2bUvSKiCgNSqh9KzNfHOpg6OvbW9gfw9fhleEqk3Th5Z3zy9ea-qXjK6YJQ1H7cL9PshuEVN6XJB1YIy-aiaMdnyeSNq8bia0bpR81YodlY9S2lLKRWc86fVGWtqqdq2mVV_VuhDDr-tsflA1jbsIP7EmAj4joDBfHDmLjjrMWWMkLB8ZrufYOuJhzxGcGQIw-gg2-ATCT25OmTrxkQ24FwYYthbbyw4W1Rd8BsCZcG5ceLJJkJn0edJLt8hWY2unzSuo00ZfCDvbiB21lv4QH79M-HJFXa2DBE8gn__vHrSg0v44vSeV7dfv_y4-Da_vF59v_h8OTdCLPOcK8qNosiXKDhKykzTgmKsWUshsYZGskaCMbxrm1aBWpsaexCyEX1XU8P5efX2qFsuuh-LFb2zyaBzxUYYk2ZKipbRuoDiCJoYUorY6yHakutBM6qn7vRWH7vTU3eaKl26K2uvTvrjeofdw9KprAK8OQGQDLi-3G9seuDaVhQZVrjXR66HoGFTgtS3NzVlnDIqGa9VIT4dCSx57S1GnUwpwZRcI5qsu2D_7_Uvc8rI2A</recordid><startdate>20060701</startdate><enddate>20060701</enddate><creator>Magni, P.</creator><creator>De Falco, G.</creator><creator>Falugi, C.</creator><creator>Franzoni, M.</creator><creator>Monteverde, M.</creator><creator>Perrone, E.</creator><creator>Sgro, M.</creator><creator>Bolognesi, C.</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>FBQ</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QH</scope><scope>7SN</scope><scope>7TN</scope><scope>7TV</scope><scope>7U7</scope><scope>7UA</scope><scope>C1K</scope><scope>F1W</scope><scope>H97</scope><scope>L.G</scope></search><sort><creationdate>20060701</creationdate><title>Genotoxicity biomarkers and acetylcholinesterase activity in natural populations of Mytilus galloprovincialis along a pollution gradient in the Gulf of Oristano (Sardinia, western Mediterranean)</title><author>Magni, P. ; De Falco, G. ; Falugi, C. ; Franzoni, M. ; Monteverde, M. ; Perrone, E. ; Sgro, M. ; Bolognesi, C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c445t-3903c90e35e43e801c67a9116b848e2a68168acc3d7679a9bc2efa4864fd20c33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Acetylcholinesterase</topic><topic>Acetylcholinesterase - analysis</topic><topic>Acetylcholinesterase - metabolism</topic><topic>Agriculture</topic><topic>Alkaline elution</topic><topic>Animal, plant and microbial ecology</topic><topic>Animals</topic><topic>Applied ecology</topic><topic>bioaccumulation</topic><topic>Biological and medical sciences</topic><topic>biomarkers</topic><topic>Biomonitoring</topic><topic>cadmium</topic><topic>DNA Damage</topic><topic>Ecotoxicology, biological effects of pollution</topic><topic>Environmental Monitoring - methods</topic><topic>enzyme activity</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>General aspects</topic><topic>genotoxicity</topic><topic>geochemistry</topic><topic>Geologic Sediments - chemistry</topic><topic>Heavy metals</topic><topic>indicator species</topic><topic>Italy</topic><topic>lead</topic><topic>Marine</topic><topic>Mediterranean Sea</topic><topic>Micronucleus test</topic><topic>Micronucleus Tests</topic><topic>Mining</topic><topic>mussels</topic><topic>Mytilus - chemistry</topic><topic>Mytilus - enzymology</topic><topic>Mytilus edulis</topic><topic>Mytilus galloprovincialis</topic><topic>sediment contamination</topic><topic>Water Pollutants, Chemical - toxicity</topic><topic>water pollution</topic><topic>Water Pollution - analysis</topic><topic>zinc</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Magni, P.</creatorcontrib><creatorcontrib>De Falco, G.</creatorcontrib><creatorcontrib>Falugi, C.</creatorcontrib><creatorcontrib>Franzoni, M.</creatorcontrib><creatorcontrib>Monteverde, M.</creatorcontrib><creatorcontrib>Perrone, E.</creatorcontrib><creatorcontrib>Sgro, M.</creatorcontrib><creatorcontrib>Bolognesi, C.</creatorcontrib><collection>AGRIS</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Aqualine</collection><collection>Ecology Abstracts</collection><collection>Oceanic Abstracts</collection><collection>Pollution Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Water Resources Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 3: Aquatic Pollution & Environmental Quality</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><jtitle>Environmental pollution (1987)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Magni, P.</au><au>De Falco, G.</au><au>Falugi, C.</au><au>Franzoni, M.</au><au>Monteverde, M.</au><au>Perrone, E.</au><au>Sgro, M.</au><au>Bolognesi, C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Genotoxicity biomarkers and acetylcholinesterase activity in natural populations of Mytilus galloprovincialis along a pollution gradient in the Gulf of Oristano (Sardinia, western Mediterranean)</atitle><jtitle>Environmental pollution (1987)</jtitle><addtitle>Environ Pollut</addtitle><date>2006-07-01</date><risdate>2006</risdate><volume>142</volume><issue>1</issue><spage>65</spage><epage>72</epage><pages>65-72</pages><issn>0269-7491</issn><eissn>1873-6424</eissn><coden>ENVPAF</coden><abstract>A year-round biomonitoring study on blue mussels (
Mytilus galloprovincialis) was carried out in 4 selected sites along the Gulf of Oristano (Sardinia, Italy): a commercial port (
Port), the outlet of the
S'Ena Arrubia and
Marceddì lagoons (in the catchment area of intensive agricultural and diary activities, and abandoned mining), and a reference site (
North). Heavy metal concentrations in sediments from
Marceddì were 2–3 to 10–20 times higher in Pb, Cd and Zn, respectively, than those found at
North and
S'Ena Arrubia. Higher values (
P
<
0.05) of micronuclei frequency were detected in mussels from
Marceddì and
Port compared to those detected in mussels from
North and
S'Ena Arrubia. DNA damage in animals from
North was significantly lower than that at the other sites. Results of acetylcholinesterase inhibition consistently showed the strongest effects in mussels from
Port and
Marceddì. Our results suggest that these biomarkers can be used in coastal marine biomonitoring as early signals of exposure and adverse effects along a pollution gradient.
Biomarkers can be useful in coastal marine biomonitoring.</abstract><cop>Oxford</cop><pub>Elsevier Ltd</pub><pmid>16289776</pmid><doi>10.1016/j.envpol.2005.09.018</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0269-7491 |
| ispartof | Environmental pollution (1987), 2006-07, Vol.142 (1), p.65-72 |
| issn | 0269-7491 1873-6424 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_19847102 |
| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Acetylcholinesterase Acetylcholinesterase - analysis Acetylcholinesterase - metabolism Agriculture Alkaline elution Animal, plant and microbial ecology Animals Applied ecology bioaccumulation Biological and medical sciences biomarkers Biomonitoring cadmium DNA Damage Ecotoxicology, biological effects of pollution Environmental Monitoring - methods enzyme activity Fundamental and applied biological sciences. Psychology General aspects genotoxicity geochemistry Geologic Sediments - chemistry Heavy metals indicator species Italy lead Marine Mediterranean Sea Micronucleus test Micronucleus Tests Mining mussels Mytilus - chemistry Mytilus - enzymology Mytilus edulis Mytilus galloprovincialis sediment contamination Water Pollutants, Chemical - toxicity water pollution Water Pollution - analysis zinc |
| title | Genotoxicity biomarkers and acetylcholinesterase activity in natural populations of Mytilus galloprovincialis along a pollution gradient in the Gulf of Oristano (Sardinia, western Mediterranean) |
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