Photoactivatable Analogues of the Initiating Substrates of RNA Polymerase II Based on Aryl Azide Derivatives of NTP γ-Amidophosphate: Synthesis and Chemical and Photochemical Reactions of Functional Groups

Photoactivatable derivatives Ar-NH-(CH sub(2)) sub(n)-NHpppB (where Ar = p-azidophenyl (A1), 5-azido-2-nitrobenzoyl (A2), or 4-azido-2,3,5,6-tetrafluorobenzoyl(A3) group; B = Ado or Guo; n = 2, 3, or 4) were synthesized. The phosphoroamidate bond stability was found to depend on the structure of bot...

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Veröffentlicht in:Russian journal of bioorganic chemistry 2005-07, Vol.31 (4), p.332-343
Hauptverfasser: Knorre, D. G., Kudryashova, N. V., Popova, T. V., Shakirov, M. M., Mal’shakova, V. S., Shpenev, O. E., Savinkova, L. K., Serebryakova, M. V., Godovikova, T. S.
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Sprache:eng
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